Methyl Bicyclo[3.1.0]hexane-6-carboxylate

Base Information

Chemical Name:Methyl Bicyclo[3.1.0]hexane-6-carboxylate
CAS No.:90199-02-3
Molecular Formula:C₈H₁₂O₂
Molecular Weight:140.182
Hs Code.:
DSSTox Substance ID:DTXSID10392786
Mol file:90199-02-3.mol

Synonyms:Methyl Bicyclo[3.1.0]hexane-6-carboxylate;90199-02-3;SCHEMBL7354850;DTXSID10392786;AKOS004115310;MethylBicyclo[3.1.0]hexane-6-carboxylate;EN300-130313

Suppliers and Price of Methyl Bicyclo[3.1.0]hexane-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methylbicyclo[3.1.0]hexane-6-carboxylate
50mg
$ 220.00

TRC
methylbicyclo[3.1.0]hexane-6-carboxylate
10mg
$ 65.00

Total 4 raw suppliers

Chemical Property of Methyl Bicyclo[3.1.0]hexane-6-carboxylate

Chemical Property:

PSA：26.30000
LogP:1.20550
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:140.083729621
Heavy Atom Count:10
Complexity:155

Purity/Quality:

97% ^*data from raw suppliers

methylbicyclo[3.1.0]hexane-6-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1C2C1CCC2

Technology Process of Methyl Bicyclo[3.1.0]hexane-6-carboxylate

There total 5 articles about Methyl Bicyclo[3.1.0]hexane-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 67-56-1
methanol

: 4971-24-8
1α,5α,6α-bicyclo[3.1.0]hexane-6-carboxylic acid

: 30648-76-1,38284-36-5,90199-02-3
exo-bicyclo[3.1.0]hexane-6-carboxylate methyl ester

Guidance literature:: With sulfuric acid; for 6h; Heating;
DOI:10.1016/j.tetlet.2005.03.209

Reference yield:

: 142-29-0
cyclopentene

: 30648-76-1,38284-36-5,90199-02-3
exo-bicyclo[3.1.0]hexane-6-carboxylate methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 96 percent / RH₂(OAc)4 / CH₂Cl₂ / 6 h / 20 °C

2.1: KOH / aq. ethanol / 6 h / Heating

2.2: 72 percent / HCl / aq. ethanol

3.1: 94 percent / H₂SO₄ / 6 h / Heating

With potassium hydroxide; sulfuric acid; dirhodium tetraacetate; In ethanol; dichloromethane;
DOI:10.1016/j.tetlet.2005.03.209

Reference yield:

: 72229-06-2
ethyl bicyclo<3.1.0>hexane-6-carboxylate

: 30648-76-1,38284-36-5,90199-02-3
exo-bicyclo[3.1.0]hexane-6-carboxylate methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: KOH / aq. ethanol / 6 h / Heating

1.2: 72 percent / HCl / aq. ethanol

2.1: 94 percent / H₂SO₄ / 6 h / Heating

With potassium hydroxide; sulfuric acid; In ethanol;
DOI:10.1016/j.tetlet.2005.03.209