[3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone

Base Information

• Chemical Name: [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone
• CAS No.: 94944-09-9
• Molecular Formula: C₁₈H₂₇NO₃Si
• Molecular Weight: 333.503

Synonyms:[3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone

Chemical Property of [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone

There total 8 articles about [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

(3S,4S)-4-Benzoyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one (94944-08-8) → [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone (94944-09-9)

Guidance literature:

With ammonium cerium(IV) nitrate; In acetonitrile; at -10 ℃;

DOI:10.1021/ja00291a069

Reference yield: 80.0%

(3R,4R)-4-Benzoyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one (94944-08-8,115404-41-6,117465-94-8,123286-16-8) → (3S,4S)-4-Benzoyl-3-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-azetidin-2-one (94944-09-9,115404-43-8,119365-78-5)

Guidance literature:

In water; acetonitrile; anodic dearylation;

DOI:10.1016/S0040-4039(00)80334-2

Reference yield: 80.0%

(3R,4S)-4-Benzoyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one (94944-08-8,115404-41-6,117465-94-8,123286-16-8) → (3R,4S)-4-Benzoyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-azetidin-2-one (94944-09-9,115404-43-8,119365-78-5)

Guidance literature:

In water; acetonitrile; anodic dearylation;

DOI:10.1016/S0040-4039(00)80334-2

upstream raw materials:

(3S,4S)-3-<(R)-1'-(dimethyl-t-butylsilyloxy)ethyl>-4-oxoazetidine-2-carboxylic acid

phenyllithium

(3S,4S)-4-Benzoyl-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-1-(4-methoxy-phenyl)-azetidin-2-one

(3S,4S,1'R) N-p-methoxyphenyl-3-(1'-hydroxyethyl)-4-benzoylazetidin-2-one

Downstream raw materials:

(2R,3S,5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-methylsulfanyl-3-nitromethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester

(5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-formyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

(5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-hydroxymethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

(3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 94944-09-9 [3S-[3α(S*),4β]]-4-benzoyl-3-[1-[[[(1,1-dimethyl-ethyl)dimethyl]silyl]oxy]ethyl]-2-azetidinone

Send

Send

Metric Ton KG G Pound L ML

Send

Send