(3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

Base Information

Chemical Name:(3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate
CAS No.:322468-36-0
Molecular Formula:C₁₉H₃₀BrO₇P
Molecular Weight:481.321
Hs Code.:

Synonyms:(3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

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Chemical Property of (3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

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Technology Process of (3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

There total 5 articles about (3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 322468-29-1
(3-O-[2-(4-isobutlyphenyl propanoyl)]-(R)-2-O-benzylglyceryl)-2-bromoethyl-methyl phosphate

: 322468-36-0
(3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

Guidance literature:: With hydrogen; palladium on activated charcoal; In dichloromethane; for 2h; under 787.563 Torr;
DOI:10.1016/S0009-3084(00)00167-5

Reference yield:

: 15687-27-1,58560-75-1
ibuprofen

: 322468-36-0
(3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / DCC; DMAP / CH₂Cl₂ / 2 h

2: 90 percent / H₂ / 10 percent Pd/C / CH₂Cl₂ / 2 h / 787.56 Torr

With dmap; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In dichloromethane;
DOI:10.1016/S0009-3084(00)00167-5

Reference yield:

: 322468-25-7
((R)-2-O-benzyl-glyceryl)-2-bromoethyl-methylphosphate

: 322468-36-0
(3-O-[2-(4-isobutylphenyl propanoyl)]-(R)-2-glyceryl)-2-bromoethyl-methyl phosphate

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / DCC; DMAP / CH₂Cl₂ / 2 h

2: 90 percent / H₂ / 10 percent Pd/C / CH₂Cl₂ / 2 h / 787.56 Torr

With dmap; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In dichloromethane;
DOI:10.1016/S0009-3084(00)00167-5