N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide

Base Information

• Chemical Name: N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide
• CAS No.: 510732-13-5
• Molecular Formula: C₂₈H₂₇NO₅
• Molecular Weight: 457.526
• Mol file: 510732-13-5.mol

Synonyms:N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide

Chemical Property of N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide

There total 2 articles about N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

phthalimide (136918-14-4,85-41-6) + 1-(2-Allyl-3-benzyloxy-4,6-dimethoxyphenyl)ethanol (225114-44-3) → N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide (510732-13-5) + 2-allyl-3-benzyloxy-4,6-dimethoxystyrene

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1016/j.tet.2003.09.001

Reference yield: 86.0%

phthalimide (136918-14-4,85-41-6) + 1-(2-Allyl-3-benzyloxy-4,6-dimethoxyphenyl)ethanol (225114-44-3) → N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide (510732-13-5)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;

DOI:10.1055/s-2002-35594

Reference yield: 61.0%

acetic anhydride (108-24-7) + methylamine (74-89-5) + N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide (510732-13-5) → N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}acetamide (510732-14-6) + N1-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}-N2-(methyl)phthalamide

Guidance literature:

methylamine; N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}phthalimide; In ethanol; water; benzene; for 2h;

acetic anhydride; With sodium sulfate; In pyridine; at 20 ℃; for 18h;

DOI:10.1016/j.tet.2003.09.001

upstream raw materials:

phthalimide

1-(2-Allyl-3-benzyloxy-4,6-dimethoxyphenyl)ethanol

Downstream raw materials:

1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethylamine

N-{1-[2-allyl-3-(benzyloxy)-4,6-dimethoxyphenyl]ethyl}acetamide

N-{1-[3-(benzyloxy)-2-(2-hydroxypropyl)-4,6-dimethoxyphenyl]ethyl}acetamide

methanesulfonic acid 2-[2-(1-acetylamino-ethyl)-6-benzyloxy-3,5-dimethoxy-phenyl]-1-methyl-ethyl ester