(4-isobutyryl)phenylazo tert-butyl sulfide

Base Information

• Chemical Name: (4-isobutyryl)phenylazo tert-butyl sulfide
• CAS No.: 159490-52-5
• Molecular Formula: C₁₄H₂₀N₂OS
• Molecular Weight: 264.392
• Mol file: 159490-52-5.mol

Synonyms:(4-isobutyryl)phenylazo tert-butyl sulfide

Chemical Property of (4-isobutyryl)phenylazo tert-butyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (4-isobutyryl)phenylazo tert-butyl sulfide

There total 2 articles about (4-isobutyryl)phenylazo tert-butyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-1-(4-nitrophenyl)propan-1-one (10326-99-5) → (4-isobutyryl)phenylazo tert-butyl sulfide (159490-52-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / SnCl₂*2H₂O / ethyl acetate / Heating

2: 1) NaNO₂, HCl, 2) 10percent NaOH / 2) EtOH

With hydrogenchloride; sodium hydroxide; tin(ll) chloride; sodium nitrite; In ethyl acetate;

DOI:10.1016/S0040-4020(01)85294-7

Reference yield:

2-methylpropan-2-thiol (75-66-1) + 1-(4-aminophenyl)-2-methylpropan-1-one (95249-12-0) → (4-isobutyryl)phenylazo tert-butyl sulfide (159490-52-5)

Guidance literature:

With hydrogenchloride; sodium hydroxide; sodium nitrite; Yield given. Multistep reaction; 2) EtOH;

DOI:10.1016/S0040-4020(01)85294-7

Reference yield: 58.0%

(4-isobutyryl)phenylazo tert-butyl sulfide (159490-52-5) + malonic acid dimethyl ester (108-59-8) → dimethyl 3-(4'-isobutyryl)phenylpropanedioate (159490-47-8)

Guidance literature:

With potassium tert-butylate; In dimethyl sulfoxide; Irradiation;

DOI:10.1016/S0040-4020(01)85294-7

upstream raw materials:

2-methylpropan-2-thiol

1-(4-aminophenyl)-2-methylpropan-1-one

2-methyl-1-(4-nitrophenyl)propan-1-one

Downstream raw materials:

methyl 3-oxo-2-(4'-isobutyryl)phenylbutanoate

3-(4'-isobutyryl)phenylpentane-1,3-dione

dimethyl 3-(4'-isobutyryl)phenylpropanedioate

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