1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

Base Information

Chemical Name:1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide
CAS No.:1176772-60-3
Molecular Formula:C₂₄H₂₂ClF₃N₄O
Molecular Weight:474.913
Hs Code.:

Synonyms:1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

Suppliers and Price of 1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

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Technology Process of 1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

There total 1 articles about 1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 3740-92-9
fenclorim

: 1141894-80-5
N-[[2-(trifluoromethyl)phenyl]methyl]-4-piperidinecarboxamide

: 1176772-60-3
1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 180 ℃; for 1h;

Reference yield: 55.0%

: 1176772-60-3
1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide

: 74-89-5
methylamine

: 76-05-1
trifluoroacetic acid

: 1312185-03-7
1-[6-(methylamino)-2-phenyl-4-pyrimidinyl]-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide trifluoroacetate

Guidance literature:: 1-(6-chloro-2-phenyl-4-pyrimidinyl)-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide; methylamine; In ethanol; at 70 ℃; for 120h;

trifluoroacetic acid; In N,N-dimethyl-formamide;