cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Base Information

Chemical Name:cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate
CAS No.:1351815-55-8
Molecular Formula:C₄₀H₅₀N₂O₅
Molecular Weight:638.847
Hs Code.:

Synonyms:cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Suppliers and Price of cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

There total 7 articles about cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 912545-09-6
2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)benzoic acid

: cyclopentyl N-piperidin-4-yl-L-leucinate dihydrochloride

: 1351815-55-8
cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; dmap; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

: 912545-08-5
2,4-bis-benzyloxy-5-isopropenyl-benzoic acid methyl ester

: 1351815-55-8
cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide; methanol / 20 h / 75 °C

1.2: 0.5 h / 20 °C

2.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dmap / dichloromethane / 18 h / 20 °C

With methanol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; dmap; In dichloromethane;

Reference yield:

: 100-39-0
benzyl bromide

: 1351815-55-8
cyclopentyl N-(1-{[2,4-bis(benzyloxy)-5-(prop-1-en-2-yl)phenyl]carbonyl}piperidin-4-yl)-L-leucinate

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium carbonate / acetonitrile / 42 h / 75 °C

2.1: potassium tert-butylate / tetrahydrofuran / 0.5 h

2.2: 0.5 h

3.1: potassium hydroxide; methanol / 20 h / 75 °C

3.2: 0.5 h / 20 °C

4.1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dmap / dichloromethane / 18 h / 20 °C

With methanol; potassium tert-butylate; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; potassium hydroxide; dmap; In tetrahydrofuran; dichloromethane; acetonitrile;