Technology Process of 3-(3,5-dimethoxyphenyl)-(6-methoxy-2-(4-methoxyphenyl)-benzofuran-4-yl) methanol
There total 8 articles about 3-(3,5-dimethoxyphenyl)-(6-methoxy-2-(4-methoxyphenyl)-benzofuran-4-yl) methanol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
dichloromethane; toluene;
at -78 ℃;
DOI:10.1039/b901911a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: copper(ll) bromide / chloroform; ethyl acetate / 16 h / Reflux
2: potassium carbonate / acetone / 3 h / 20 °C
3: methanesulfonic acid / dichloromethane / 30 h / 40 °C
4: potassium acetate; palladium diacetate; N,N-dimethyl acetamide / 18 h / 120 °C / Sealed tube
5: magnesium; ammonium chloride / tetrahydrofuran; methanol / 3 h / 0 - 20 °C
With
methanesulfonic acid; N,N-dimethyl acetamide; potassium acetate; palladium diacetate; potassium carbonate; ammonium chloride; magnesium; copper(ll) bromide;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; ethyl acetate; acetone;
DOI:10.1055/s-0035-1561419
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / acetone / 3 h / 20 °C
2: methanesulfonic acid / dichloromethane / 30 h / 40 °C
3: potassium acetate; palladium diacetate; N,N-dimethyl acetamide / 18 h / 120 °C / Sealed tube
4: magnesium; ammonium chloride / tetrahydrofuran; methanol / 3 h / 0 - 20 °C
With
methanesulfonic acid; N,N-dimethyl acetamide; potassium acetate; palladium diacetate; potassium carbonate; ammonium chloride; magnesium;
In
tetrahydrofuran; methanol; dichloromethane; acetone;
DOI:10.1055/s-0035-1561419
