1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

Base Information

Chemical Name:1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione
CAS No.:945257-71-6
Molecular Formula:C₁₈H₁₅ClF₃N₃O₄S
Molecular Weight:461.849
Hs Code.:

Synonyms:1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

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Chemical Property of 1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

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Technology Process of 1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

There total 1 articles about 1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101990-73-2
2-chloro-pyridin-4-ylmethyl chloride

: 945257-72-7
5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}-imidazolidine-2,4-dione

: 945257-71-6
1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

Guidance literature:: With sodium hydride; In tetrahydrofuran; for 24h; Heating / reflux;

Reference yield:

: 945257-71-6
1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

: 598-50-5
N-Methylurea

: 945257-70-5
1-{4-[(5,5-dimethyl-2,4-dioxo-3-{4-[(trifluoromethyl)-sulfonyl]phenyl}imidazolidin-1-yl)methyl]pyridin-2-yl}-3-methylurea

Guidance literature:: With caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; for 2.5h; Heating / reflux;

Reference yield:

: 60-35-5
acetamide

: 945257-71-6
1-[(2-chloropyridin-4-yl)methyl]-5,5-dimethyl-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidine-2,4-dione

: 1082336-75-1
N-{4-[(5,5-dimethyl-2,4-dioxo-3-{4-[(trifluoromethyl)sulfonyl]phenyl}imidazolidin-1-yl)methyl]-pyridin-2-yl}acetamide

Guidance literature:: With caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; for 5h; Heating / reflux;