acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Base Information

Chemical Name:acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester
CAS No.:1026680-98-7
Molecular Formula:C₁₇H₁₃ClN₂O₃S
Molecular Weight:360.821
Hs Code.:

Synonyms:acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Suppliers and Price of acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

There total 9 articles about acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-36-5
acetyl chloride

: 247080-36-0
2-(4-amino-3-chloro-phenyl)-benzothiazol-4-ol

: 1026680-98-7
acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Guidance literature:: With triethylamine; In dichloromethane; at 5 ℃; for 1h;
DOI:10.1021/jm990104o

Reference yield:

: 24367-70-2
N-(2-methoxyphenyl)-4-nitrothiobenzamide

: 1026680-98-7
acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Guidance literature:: Multi-step reaction with 6 steps

1: 68 percent / potassium ferricyanide; aq. NaOH / ethanol / 0.5 h / 90 °C

2: 72 percent / SnCl₂*2H₂O / ethanol / 2 h / Heating

3: 30 percent / ICl; AcOH / 2 h / 25 °C

4: 34 percent / CuCl / dimethylformamide / 15 h / Heating

5: 69 percent / boron tribromide / CH₂Cl₂ / 1 h / 25 °C

6: triethylamine / CH₂Cl₂ / 1 h / 5 °C

With sodium hydroxide; Iodine monochloride; boron tribromide; acetic acid; triethylamine; copper(l) chloride; tin(ll) chloride; potassium hexacyanoferrate(III); In ethanol; dichloromethane; N,N-dimethyl-formamide; 1: Jacobson cyclization / 2: Reduction / 3: Iodination / 4: Substitution / 5: demethylation / 6: Acetylation;
DOI:10.1021/jm990104o

Reference yield:

: 24367-68-8
N-(2-methoxyphenyl)-4-nitrobenzamide

: 1026680-98-7
acetic acid 2-(4-acetylamino-3-chloro-phenyl)-benzothiazol-4-yl ester

Guidance literature:: Multi-step reaction with 7 steps

1: 68 percent / Lawesson's reagent; HMPA / 6 h / 100 °C

2: 68 percent / potassium ferricyanide; aq. NaOH / ethanol / 0.5 h / 90 °C

3: 72 percent / SnCl₂*2H₂O / ethanol / 2 h / Heating

4: 30 percent / ICl; AcOH / 2 h / 25 °C

5: 34 percent / CuCl / dimethylformamide / 15 h / Heating

6: 69 percent / boron tribromide / CH₂Cl₂ / 1 h / 25 °C

7: triethylamine / CH₂Cl₂ / 1 h / 5 °C

With Lawessons reagent; N,N,N,N,N,N-hexamethylphosphoric triamide; sodium hydroxide; Iodine monochloride; boron tribromide; acetic acid; triethylamine; copper(l) chloride; tin(ll) chloride; potassium hexacyanoferrate(III); In ethanol; dichloromethane; N,N-dimethyl-formamide; 1: Substitution / 2: Jacobson cyclization / 3: Reduction / 4: Iodination / 5: Substitution / 6: demethylation / 7: Acetylation;
DOI:10.1021/jm990104o