O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate

Base Information

• Chemical Name: O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate
• CAS No.: 165282-30-4
• Molecular Formula: C₄₁H₅₃N₅O₁₃
• Molecular Weight: 823.898

Synonyms:O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate

Chemical Property of O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate

There total 3 articles about O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

ethanol (64-17-5) + O1,O5-diallyl L-glutamate + O1.3,O4.3-diallyl N2.1,N6.1-di-Cbz-L-lysylglycyl-L-aspartate (165282-29-1) → O4.3,O5.4-diallyl O1.4-ethyl N2.1,N6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate (165282-30-4)

Guidance literature:

at 37 ℃; for 40h; immobilized subtilisin;

Reference yield:

Nα,Nξ-di-Cbz-L-lysine ethyl ester (83173-67-5) → O4.3,O5.4-diallyl O1.4-ethyl N2.1,N6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate (165282-30-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 82 percent / 1.) NaOH/EtOH, K₂CO₃, KHCO₃, / ethanol / 40 h / 37 °C / chymopapain, CHES buffer, EDTA, dithiothreitol

2: 84 percent / ethanol / 2 h / 37 °C / papaya protease IV, CHES buffer, EDTA, dithiothreitol

3: 76 percent / 40 h / 37 °C / immobilized subtilisin

With sodium hydroxide; ethanol; potassium carbonate; potassium hydrogencarbonate; In ethanol;

Reference yield:

Nα,Nξ-di-Cbz-L-lysylglycine ethyl ester (13567-34-5) → O4.3,O5.4-diallyl O1.4-ethyl N2.1,N6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate (165282-30-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / ethanol / 2 h / 37 °C / papaya protease IV, CHES buffer, EDTA, dithiothreitol

2: 76 percent / 40 h / 37 °C / immobilized subtilisin

In ethanol;

upstream raw materials:

ethanol

O^1.3,O^4.3-diallyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-L-aspartate

N_α,N_ξ-di-Cbz-L-lysylglycine ethyl ester

N_α,N_ξ-di-Cbz-L-lysine ethyl ester

Downstream raw materials:

O^1.4-ethyl dihydrogen N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate

O^5.5-ethyl dihydrogen N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-α-L-glutamyl-α-L-glutamyl-L-seryl-L-leucyl-L-alaninamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 165282-30-4 O^4.3,O^5.4-diallyl O^1.4-ethyl N^2.1,N^6.1-di-Cbz-L-lysylglycyl-α-L-aspartyl-L-glutamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send