(4-Chlorophenyl)-difluoroacetic acid

Base Information

• Chemical Name: (4-Chlorophenyl)-difluoroacetic acid
• CAS No.: 130754-19-7
• Molecular Formula: C₁₀H₉ClF₂O₂
• Molecular Weight: 234.63
• Hs Code.: 2916391000
• Mol file: 130754-19-7.mol

Synonyms:ethyl 4-chlorophenyl-2,2-difluoroacetate

Chemical Property of (4-Chlorophenyl)-difluoroacetic acid

Chemical Property:

• Boiling Point: 267.1±35.0 °C(Predicted)
• Density: 1.286±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl2-(4-chlorophenyl)-2,2-difluoroacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-Chlorophenyl)-difluoroacetic acid

There total 11 articles about (4-Chlorophenyl)-difluoroacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

→ ethyl 4-chlorophenyl-2,2-difluoroacetate (130754-19-7)

Guidance literature:

With copper; In dimethyl sulfoxide; at 30 - 50 ℃; for 16h; Inert atmosphere;

Reference yield: 79.0%

1-Chloro-4-iodobenzene (637-87-6) + Ethyl bromodifluoroacetate (667-27-6) → ethyl 4-chlorophenyl-2,2-difluoroacetate (130754-19-7)

Guidance literature:

With copper; In dimethyl sulfoxide; at 55 ℃; for 12h; Inert atmosphere;

DOI:10.1002/jhet.4367

Reference yield:

ethyl 2-(4-chlorophenyl)-2-oxoacetate (34966-48-8) → ethyl 4-chlorophenyl-2,2-difluoroacetate (130754-19-7)

Guidance literature:

With diethylamino-sulfur trifluoride; In dichloromethane; at 20 ℃; for 16h;

upstream raw materials:

4-chloro-benzeneacetic acid, ethyl ester

4-chlorophenylacetic Acid

(4-chlorphenyl)magnesium bromide

1-Chloro-4-iodobenzene

Downstream raw materials:

2-(4-chlorophenyl)-2,2-difluoroethanol

2-(4-Chloro-phenyl)-2,2-difluoro-acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 130754-19-7 (4-Chlorophenyl)-difluoroacetic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send