N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

Base Information

Chemical Name:N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide
CAS No.:875917-30-9
Molecular Formula:C₁₉H₂₄N₂O₂S
Molecular Weight:344.478
Hs Code.:

Synonyms:N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

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Chemical Property of N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

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Technology Process of N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

There total 1 articles about N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 875917-29-6
N-[5-(3-cyanophenyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide

: 875917-30-9
N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

Guidance literature:: N-[5-(3-cyanophenyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 2.25h; Heating / reflux;

With water; In tetrahydrofuran; at 20 ℃;

Reference yield: 55.0%

: 875917-30-9
N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

: 124-63-0
methanesulfonyl chloride

: N-[5-(3-{[(methylsulfonyl)amino]methyl}phenyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 1h;

Reference yield: 19.0%

: 875917-30-9
N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide

: 4635-59-0
4-Chlorobutanoyl chloride

: N-(5-{3-[(2-oxo-1-pyrrolidinyl)methyl]phenyl}-2,3-dihydro-1H-inden-2-yl)-2-propanesulfonamide

Guidance literature:: N-{5-[3-(aminomethyl)phenyl]-2,3-dihydro-1H-inden-2-yl}-2-propanesulfonamide; 4-Chlorobutanoyl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 1h;

With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 2h;