2,5-Dioxo-bicyclo[2.2.2]octane-1,4-dicarboxylic acid diMethyl ester

Base Information

Chemical Name:2,5-Dioxo-bicyclo[2.2.2]octane-1,4-dicarboxylic acid diMethyl ester
CAS No.:57293-62-6
Molecular Formula:C₁₂H₁₄O₆
Molecular Weight:254.24
Hs Code.:
Mol file:57293-62-6.mol

Synonyms:dimethyl 1,4-dioxobicyclo<2.2.2>octane-2,5-dicarboxylate

Suppliers and Price of 2,5-Dioxo-bicyclo[2.2.2]octane-1,4-dicarboxylic acid diMethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 5 raw suppliers

Chemical Property of 2,5-Dioxo-bicyclo[2.2.2]octane-1,4-dicarboxylic acid diMethyl ester

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2,5-Dioxo-bicyclo[2.2.2]octane-1,4-dicarboxylic acid diMethyl ester

There total 2 articles about 2,5-Dioxo-bicyclo[2.2.2]octane-1,4-dicarboxylic acid diMethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 6289-46-9
dimethyl 2,5-dioxocyclohexane-1,4-dicarboxylate

: 106-93-4
ethylene dibromide

: 57293-62-6
dimethyl 1,4-dioxobicyclo<2.2.2>octane-2,5-dicarboxylate

Guidance literature:: dimethyl 2,5-dioxocyclohexane-1,4-dicarboxylate; With sodium hydride; In 1,2-dimethoxyethane; at 20 ℃; Inert atmosphere; Reflux;

ethylene dibromide; Inert atmosphere; Reflux;
DOI:10.1002/anie.200907033

Reference yield:

: 57293-62-6
dimethyl 1,4-dioxobicyclo<2.2.2>octane-2,5-dicarboxylate

Guidance literature:: aus Bicyclo<2.2.2>octan-2,5-dion-1,4-dicarbonsaeure (4);
DOI:10.1016/0040-4020(75)87016-5

Reference yield:

: 57293-62-6
dimethyl 1,4-dioxobicyclo<2.2.2>octane-2,5-dicarboxylate

: 1459-96-7
dimethyl bicyclo[2.2.2]octane-1,4-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 88.9 percent / BF₃*Et₂O / acetic acid / 24 h

2: 89.2 percent / EtOH / Raney nickel-W₂ / 96 h / Heating

With ethanol; boron trifluoride diethyl etherate; Raney nickel-W₂; In acetic acid;
DOI:10.1055/s-1996-4152