2,4-diphenyl-5,6-dihydrobenzoquinazoline

Base Information

• Chemical Name: 2,4-diphenyl-5,6-dihydrobenzoquinazoline
• CAS No.: 148256-51-3
• Molecular Formula: C₂₄H₁₈N₂
• Molecular Weight: 334.42
• Mol file: 148256-51-3.mol

Synonyms:2,4-diphenyl-5,6-dihydrobenzoquinazoline

Chemical Property of 2,4-diphenyl-5,6-dihydrobenzoquinazoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-diphenyl-5,6-dihydrobenzoquinazoline

There total 3 articles about 2,4-diphenyl-5,6-dihydrobenzoquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1,2,3,4-Tetrahydro-1-naphthol (529-33-9) + benzamidin (618-39-3) + benzyl alcohol (100-51-6,185532-71-2) → 2,4-diphenyl-5,6-dihydrobenzoquinazoline (148256-51-3)

Guidance literature:

With C₄₉H₄₀N₃O₂P₂Ru⁽¹⁺⁾*Cl^(1-); potassium tert-butylate; In 1,4-dioxane; at 120 ℃; for 24h; Sealed tube; Schlenk technique;

DOI:10.1039/c9dt04040d

Reference yield: 78.0%

2,4-diphenyl-3,4,5,6-tetrahydrobenzoquinazoline (106319-25-9) → 2,4-diphenyl-5,6-dihydrobenzoquinazoline (148256-51-3)

Guidance literature:

With potassium hydroxide; potassium hexacyanoferrate(III); In water; benzene; Ambient temperature;

DOI:10.1007/BF00808676

Reference yield: 65.0%

trifluoromethylsulfonic anhydride (358-23-6) + benzonitrile (100-47-0) + 3,4-dihydronaphthalene-1(2H)-one (529-34-0) → 3,4-dihydro-1-naphthyl triflate (123994-49-0) + 2,4-diphenyl-5,6-dihydrobenzoquinazoline (148256-51-3)

Guidance literature:

In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.tet.2006.01.010

upstream raw materials:

2,4-diphenyl-3,4,5,6-tetrahydrobenzoquinazoline

trifluoromethylsulfonic anhydride

benzonitrile

3,4-dihydronaphthalene-1(2H)-one

Downstream raw materials:

1,3-diphenylbenzo[h]quinazoline