2-Piperidinone,1-[(1R)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-,(3E)-

Base Information

Chemical Name:2-Piperidinone,1-[(1R)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-,(3E)-
CAS No.:870846-02-9
Molecular Formula:C₂₅H₂₆FN₃O₂
Molecular Weight:419.499
Hs Code.:
Mol file:870846-02-9.mol

Synonyms:2-PIPERIDINONE,1-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-3-[[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]METHYLENE]-,(3E)-

Suppliers and Price of 2-Piperidinone,1-[(1R)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-,(3E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3E)-1-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-3-[[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]METHYLENE]-2-PIPERIDINONE 95.00%
5MG
$ 501.05

Total 0 raw suppliers

Chemical Property of 2-Piperidinone,1-[(1R)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-,(3E)-

Chemical Property:

Purity/Quality:: (3E)-1-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-3-[[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]METHYLENE]-2-PIPERIDINONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Piperidinone,1-[(1R)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-,(3E)-

There total 16 articles about 2-Piperidinone,1-[(1R)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-,(3E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 937026-29-4
acetic acid {1-[(1S)-1-(4-fluorophenyl)ethyl]-2-oxopiperidin-3-yl}[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methyl ester

: 870843-42-8,870846-02-9
(E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one

Guidance literature:: With sodium t-butanolate; In toluene; at -13 ℃; for 2.61667h; Product distribution / selectivity;

Reference yield: 87.0%

: 870837-18-6
3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde

: 937026-11-4
1-[(S)-1-(4-fluorophenyl)ethyl]piperidin-2-one

: 870843-42-8,870846-02-9
(E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one

Guidance literature:: 1-[(S)-1-(4-fluorophenyl)ethyl]piperidin-2-one; With n-butyllithium; diisopropylamine; In tetrahydrofuran; cyclohexane; toluene; at -20 ℃; for 1.76667 - 148h;

3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzaldehyde; In tetrahydrofuran; cyclohexane; toluene; at -20 ℃; for 1.66667 - 2.66667h;

With acetic anhydride; sodium t-butanolate; more than 3 stages; Product distribution / selectivity;

Reference yield: 81.0%

: 937026-24-9
1-[(S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzoyl]piperidin-2-one

: 870843-42-8,870846-02-9
(E)-1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one

Guidance literature:: 1-[(S)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzoyl]piperidin-2-one; With sodium tetrahydroborate; In isopropyl alcohol; at 20 ℃; for 12h;

With water; In isopropyl alcohol; toluene; Product distribution / selectivity;