Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester

Base Information

• Chemical Name: Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester
• CAS No.: 627084-22-4
• Molecular Formula: C₄₉H₈₁O₇P
• Molecular Weight: 813.152
• Mol file: 627084-22-4.mol

Synonyms:Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester

Chemical Property of Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester

There total 1 articles about Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,2-di-O-palmitoyl-sn-glycerol (6076-30-8) + Dibenzyl N,N-diisopropylphosphoramidite (108549-23-1) → Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester (627084-22-4)

Guidance literature:

With 1H-tetrazole; In dichloromethane; at 23 ℃; for 0.5h;

DOI:10.1016/S0040-4039(97)00950-7 DOI:10.1016/S0960-894X(97)00370-3

Reference yield: 88.0%

Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester (627084-22-4) + L-1,2-O-cyclohexylidene-5,6-di-O-(o-xylylenephosphoryl)-myo-inositol (524047-36-7) → C70H107O19P3

Guidance literature:

With 2,6-dimethylpyridine; pyridinium hydrobromide perbromide; for 1.5h;

DOI:10.1246/cl.2003.46

Reference yield: 87.0%

Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester (627084-22-4) + 5-dibenzyl L-1,2-O-cyclohexylidene-6-O-levulinoyl-myo-inositol phosphate (608880-25-7) → C73H112O18P2

Guidance literature:

With 2,6-dimethylpyridine; pyridinium hydrobromide perbromide; In dichloromethane; at -42 - 0 ℃;

DOI:10.1246/cl.2003.724

upstream raw materials:

1,2-di-O-palmitoyl-sn-glycerol

Dibenzyl N,N-diisopropylphosphoramidite