6076-30-8

Basic information

• Product Name: 2 3-DIPALMITOYL-SN-GLYCEROL*
• Synonyms: (r)-1,2-dipalmitin;(R)-1,2-Dipalmitin, (R)-Glycerol 1,2-dipalmitate;(+)-D-1,2-Dipalmitin;(R)-Propane-1,2,3-triol 1,2-dipalmitate;1-O,2-O-Dipalmitoyl-D-glycerol;2-O,3-O-Dipalmitoyl-L-glycerol;(R)-Glycerol 1,2-dipalmitate
• CAS NO: 6076-30-8
• Molecular Formula: C₃₅H₆₈O₅
• Molecular Weight: 568.91
• Mol File: 6076-30-8.mol
• Article Data: 13

Chemical Properties

• Melting Point: 67-70 °C
• Appearance: /
• Storage Temp.: −20°C
• CAS DataBase Reference: 2 3-DIPALMITOYL-SN-GLYCEROL*(CAS DataBase Reference)
• NIST Chemistry Reference: 2 3-DIPALMITOYL-SN-GLYCEROL*(6076-30-8)
• EPA Substance Registry System: 2 3-DIPALMITOYL-SN-GLYCEROL*(6076-30-8)

Safety Data

• WGK Germany: 3
• F: 10
• Hazardous Substances Data: 6076-30-8(Hazardous Substances Data)

Usage

Uses

2,3-Dipalmitoyl-sn-glycerol is a protein kinase C (PKC) activator.

Upstream product

• 30563-16-7 2,3-dipalmitoyl-1-triphenylmethyl-sn-glycerol 
• 90365-30-3 1-O-benzyl-2,3-di-O-hexadecanoyl-sn-glycerol 
• 107228-48-8 S-(-)-2,2'-dinitrobiphenyl-6,6'-dicarbonsaeure-di-(1,2-dihexadecylcarbonyloxy-propyl)-ester 
• 858345-18-3 2,3-di-O-palmitoyl-1-O-(4'-methoxyphenyl)-sn-glycerol 
• 143003-65-0 (2R)-3-(benzyloxy)-2-hydroxypropyl hexadecanoate 
• 112-67-4 n-hexadecanoyl chloride 
• 1210796-90-9 (R)-1,2-dipalmitoyloxy-3-(2-methoxyphenoxy)propane 

Downstream Products

• 89291-52-1 Hexadecanoic acid (S)-2-[(benzotriazol-1-yloxy)-(2-chloro-phenoxy)-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester 
• 120595-85-9 1,2-di-O-hexadacanoyl-sn-glycerobenzyl (N,N-diisopropylamino)phopshoramidite 
• 58560-71-7 dipalmitoylphosphatidic acid 
• 627084-22-4 Hexadecanoic acid (S)-2-(bis-benzyloxy-phosphanyloxy)-1-hexadecanoyloxymethyl-ethyl ester 
• 102491-55-4 2,3-dihexadecanoyl-1-cis-octadec-9,12-dienoyl-sn-glycerol 
• 53023-10-2 1-oleoyl-2,3-dipalmitoyl-sn-glycerol 
• 89291-53-2 Hexadecanoic acid (S)-2-{(2-chloro-phenoxy)-[(2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-(4-oxo-pentanoyloxy)-tetrahydro-furan-2-ylmethoxy]-phosphoryloxy}-1-hexadecanoyloxymethyl-ethyl ester 
• 124402-60-4 Hexadecanoic acid (S)-1-hexadecanoyloxymethyl-2-(hydroxy-phenoxy-phosphoryloxy)-ethyl ester 
• 6367-90-4 Hexadecanoic acid (S)-2-[((S)-2,3-bis-hexadecanoyloxy-propoxy)-phenoxy-phosphoryloxy]-1-hexadecanoyloxymethyl-ethyl ester 
• 79907-73-6 L-2.3-Dipalmitoyl-glycerin-phosphorsaeure-1-mono-(β-brom-aethylester) 
• 115290-75-0 C₄₄H₇₉N₃O₁₅P₂^(2-)*2Na⁽¹⁺⁾ 

Relevant articles and documents

Nucleosides and nucleotides. 155. Synthesis, antitumor effects, and possible enzymatic activation mechanism of 5'-phosphatidyl-2'-deoxy-2'-methylenecytidine (DMDC)

2'-Deoxy-2'-methylenecytidine (DMDC, 1) and its 5-fluoro congener (5-F-DMDC, 2), potent antitumor nucleosides developed by us, were efficiently converted to their 5'-phosphatidyl derivatives bearing palmitoyl residues (3 and 4, respectively) as novel antitumor phospholipids by phospholipase D-catalyzed trans-phosphatidylation. These phospholipids 3 and 4, administered i.p., remarkably prolonged the life-span of mice which were i.p.-inoculated with M5076 sarcoma, and the effects were clearly superior to that of DMDC. Compound 3 was a good substrate for phospholipase A2 from bovine pancreas as well as phospholipase D from Streptomyces, while it was slightly hydrolyzed by phospholipase C from Bacillus cereus.

Synthesis of enantiopure structured triacylglycerols

The synthesis of nine enantiopure structured triacylglycerols (TAGs) of the AAB type is described, all possessing the (S)-absolute configuration. Six of them possess one saturated and two identical unsaturated fatty acyl chains, whereas the remaining three possess two identical saturated fatty acids along with one unsaturated fatty acid. The former group was synthesized by a five-step chemoenzymatic route involving a highly regioselective immobilized Candida antarctica lipase, starting from enantiopure (R)-solketal. The second group was prepared by a fully chemical five-step approach based on the same chiral precursor. Such enantiopure TAGs are strongly required as standards for the enantiospecific analysis of intact TAGs in fats and oils.

Glycerophosphoric acid ester derivative having polyfunctional metal chelate structure

A compound represented by the following general formula (I), or a salt thereof: wherein R1 and R2 independently represent a substituted or unsubstituted alkyl or alkenyl group having 8 to 30 carbon atoms; L represents a divalent bridging group (L is constituted by atoms selected from the group consisting of carbon atom, oxygen atom, nitrogen atom and hydrogen atom, wherein the total number of atoms constituting L and selected from the group consisting of carbon atom, oxygen atom and nitrogen atom is 4 to 15); and Ch represents a chelate forming moiety containing 3 or more nitrogen atoms. A compound suitable for a liposome contrast medium for performing lesion-selective imaging is provided.