Technology Process of C8H7IO4
There total 5 articles about C8H7IO4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
4-amino-2-hydroxy-3-methoxybenzoic acid;
With
hydrogenchloride; sodium nitrite;
In
water; acetonitrile;
at -20 ℃;
for 0.333333h;
With
potassium iodide;
In
water; acetonitrile;
at -20 - 25 ℃;
DOI:10.1021/acs.orglett.1c02312
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium nitrate; trifluoroacetic acid / -45 - 25 °C
2.1: sodium dihydrogenphosphate / dichloromethane / 0.25 h / -15 °C
2.2: 3 h / 25 °C
3.1: potassium carbonate / water; tetrahydrofuran; methanol / 6 h / 25 °C
4.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 48 h / 25 °C
5.1: hydrogenchloride; sodium nitrite / water; acetonitrile / 0.33 h / -20 °C
5.2: -20 - 25 °C
With
hydrogenchloride; sodium dihydrogenphosphate; palladium 10% on activated carbon; hydrogen; potassium carbonate; potassium nitrate; trifluoroacetic acid; sodium nitrite;
In
tetrahydrofuran; methanol; dichloromethane; water; acetonitrile;
DOI:10.1021/acs.orglett.1c02312
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / water; tetrahydrofuran; methanol / 6 h / 25 °C
2.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 48 h / 25 °C
3.1: hydrogenchloride; sodium nitrite / water; acetonitrile / 0.33 h / -20 °C
3.2: -20 - 25 °C
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; sodium nitrite;
In
tetrahydrofuran; methanol; water; acetonitrile;
DOI:10.1021/acs.orglett.1c02312
