2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside

Base Information

• Chemical Name: 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside
• CAS No.: 1277151-59-3
• Molecular Formula: C₅₀H₅₃BrF₁₇O₁₀PSi
• Molecular Weight: 1275.9
• Mol file: 1277151-59-3.mol

Synonyms:2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside

Chemical Property of 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside

There total 6 articles about 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C50H53BrF17O9PSi → 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside (1277151-59-3)

Guidance literature:

With tert.-butylhydroperoxide; In nonane; dichloromethane; acetonitrile; Inert atmosphere;

DOI:10.1021/ol2003435

Reference yield:

2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decan-1-ol (89807-86-3) → 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside (1277151-59-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 1H-tetrazole / tetrahydrofuran; dichloromethane / 20 °C / Inert atmosphere

2: 1H-tetrazole / dichloromethane; acetonitrile / 20 °C / Inert atmosphere

3: tert.-butylhydroperoxide / nonane; dichloromethane; acetonitrile / Inert atmosphere

With 1H-tetrazole; tert.-butylhydroperoxide; In tetrahydrofuran; nonane; dichloromethane; acetonitrile;

DOI:10.1021/ol2003435

Reference yield:

benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl diisopropylphosphoramidite (1277151-49-1) → 2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-3-O-p-methoxybenzyl-β-D-galactopyranoside (1277151-59-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1H-tetrazole / dichloromethane; acetonitrile / 20 °C / Inert atmosphere

2: tert.-butylhydroperoxide / nonane; dichloromethane; acetonitrile / Inert atmosphere

With 1H-tetrazole; tert.-butylhydroperoxide; In nonane; dichloromethane; acetonitrile;

DOI:10.1021/ol2003435

upstream raw materials:

benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl diisopropylphosphoramidite

2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-decan-1-ol

benzyl-N,N,N',N'-tetraisopropylphosphorodiamidite

2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-3-O-p-methoxybenzyl-β-D-galactopyranoside

Downstream raw materials:

2-(trimethylsilyl)ethyl 2,4-di-O-benzyl-6-(benzyl 2-bromo-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl phosphate)-β-D-galactopyranoside