(2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

Base Information

Chemical Name:(2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete
CAS No.:100431-34-3
Molecular Formula:C₁₅H₂₀ClNO₃
Molecular Weight:297.782
Hs Code.:

Synonyms:(2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

Suppliers and Price of (2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

There total 2 articles about (2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 2985-33-3
monoethyl methylmalonate

: 100431-27-4
1-chloro-2(R)-amino-phenylpropane hydrochloride

: 100431-34-3
(2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

Guidance literature:: With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; chloroform; Ambient temperature;
DOI:10.1021/jm00155a027

Reference yield:

: 5267-64-1
(R)-2-amino-3-phenylpropanol

: 100431-34-3
(2RS)-ethyl-3-<<(1R)-1-(chloromethyl)-2-phenylethyl>amino>-2-methyl-3-oxopropanoete

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / SOCl₂ / dimethylformamide / 2 h / 120 °C

2: 85 percent / triethylamine, 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide / CHCl₃; tetrahydrofuran / Ambient temperature

With thionyl chloride; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jm00155a027