methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Base Information

Chemical Name:methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate
CAS No.:959991-55-0
Molecular Formula:C₂₂H₂₅Cl₂N₃O₃
Molecular Weight:450.365
Hs Code.:

Synonyms:methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Suppliers and Price of methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

There total 3 articles about methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 959991-54-9
methyl 4-{4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

: 959991-55-0
methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Guidance literature:: methyl 4-{4-[(tert-butoxycarbonyl)amino]piperidin-1-yl}-N-(2,6-dichlorobenzoyl)-L-phenylalaninate; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

With ammonia; In methanol; dichloromethane;

Reference yield:

: 232276-45-8
N-(2,6-dichlorobenzoyl)-O-(trifluoromethanesulfonyl)-L-tyrosine methyl ester

: 959991-55-0
methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / toluene / 10 h / 100 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

With caesium carbonate; trifluoroacetic acid; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In dichloromethane; toluene;

Reference yield:

: 73874-95-0
(piperidin-4-yl)carbamic acid tert-butyl ester

: 959991-55-0
methyl 4-(4-aminopiperidin-1-yl)-N-(2,6-dichlorobenzoyl)-L-phenylalaninate

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate / 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium⁽⁰⁾ / toluene / 10 h / 100 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

With caesium carbonate; trifluoroacetic acid; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In dichloromethane; toluene;