(1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate

Base Information

• Chemical Name: (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate
• CAS No.: 696628-97-4
• Molecular Formula: C₄₁H₆₅ClN₂O₈
• Molecular Weight: 749.429

Synonyms:(1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate

Chemical Property of (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate

There total 4 articles about (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

p-chlorphenylisocyanate (104-12-1) + ethyl 6-oleylamino-6,7-dideoxy-1,2:3,4-di-O-isopropylidene-L-glycero-α-D-galacto-octopyranuronate (696628-43-0) → (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N3-(4-chlorophenyl)-N1-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate (696628-97-4)

Guidance literature:

In dichloromethane; at 25 ℃; for 4h;

DOI:10.1081/CAR-120030140

Reference yield:

(3aR,5S,5aR,8aS,8bR)-2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-carbaldehyde (4933-77-1) → (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N3-(4-chlorophenyl)-N1-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate (696628-97-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 85 percent / lithium hydroxide monohydrate / tetrahydrofuran / 10 h

2: ethanol / 16 h / 30 °C

3: 95 percent / CH₂Cl₂ / 4 h / 25 °C

With lithium hydroxide; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1081/CAR-120030140

Reference yield:

1,2:3,4-di-O-isopropylidene-α-D-galactopyranose (4064-06-6) → (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N3-(4-chlorophenyl)-N1-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate (696628-97-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 56.4 percent / pyridinium chlorochromate; molecular sieves 4 Angstroem / CH₂Cl₂ / 2 h

2: 85 percent / lithium hydroxide monohydrate / tetrahydrofuran / 10 h

3: ethanol / 16 h / 30 °C

4: 95 percent / CH₂Cl₂ / 4 h / 25 °C

With lithium hydroxide; 4 A molecular sieve; pyridinium chlorochromate; In tetrahydrofuran; ethanol; dichloromethane;

DOI:10.1081/CAR-120030140

upstream raw materials:

p-chlorphenylisocyanate

ethyl 6-oleylamino-6,7-dideoxy-1,2:3,4-di-O-isopropylidene-L-glycero-α-D-galacto-octopyranuronate

(3aR,5S,5aR,8aS,8bR)-2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b;4',5'-d]pyran-5-carbaldehyde

(E)-ethyl 6,7-dideoxy-1,2:3,4-di-O-isopropylidene-α-D-galacto-6-eno-octopyranuronate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 696628-97-4 (1R,2R,3S,4S,5R,6S) ethyl [6,7-dideoxy-6-{N³-(4-chlorophenyl)-N¹-oleyl-(1-ureidyl)}-1,2:3,4-di-O-isopropylidene-tetrahydro-1,5-octopyranos-5-yl]-uronate

Send

Send

Metric Ton KG G Pound L ML

Send

Send