C₁₈H₁₈F₂N₄OS

Base Information

Chemical Name:C₁₈H₁₈F₂N₄OS
CAS No.:1200495-69-7
Molecular Formula:C₁₈H₁₈F₂N₄OS
Molecular Weight:376.43
Hs Code.:

C<sub>18</sub>H<sub>18</sub>F<sub>2</sub>N<sub>4</sub>OS

Synonyms:C₁₈H₁₈F₂N₄OS

Suppliers and Price of C₁₈H₁₈F₂N₄OS

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₁₈H₁₈F₂N₄OS

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₁₈H₁₈F₂N₄OS

There total 8 articles about C₁₈H₁₈F₂N₄OS which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1200498-32-3
C₂₃H₂₆F₂N₄O₃S

: 1200495-69-7
C₁₈H₁₈F₂N₄OS

Guidance literature:: C₂₃H₂₆F₂N₄O₃S; With trifluoroacetic acid; In chloroform; at 20 ℃; for 3h;

With sodium carbonate; In water;

Reference yield:

: 348-57-2
2,4-difluorobromobenzene

: 1200495-69-7
C₁₈H₁₈F₂N₄OS

Guidance literature:: Multi-step reaction with 8 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 1 h / -78 °C

1.2: -78 - 0 °C

1.3: 0 °C

2.1: diisopropylamine; n-butyllithium / tetrahydrofuran / -78 °C

2.2: 3 h / -78 - 0 °C

2.3: 0 °C

3.1: potassium hydroxide; water / ethanol / 4 h / Reflux

4.1: hydrogenchloride / acetic acid / 40 - 50 °C

5.1: trifluoroacetic acid; sulfuric acid / 7 h / 60 °C

6.1: tetrahydrofuran / 1 h / 20 °C

7.1: sodium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; water / 0.5 h / 70 °C / microwave

8.1: trifluoroacetic acid / chloroform / 3 h / 20 °C

With hydrogenchloride; n-butyllithium; sulfuric acid; water; sodium carbonate; diisopropylamine; trifluoroacetic acid; potassium hydroxide; lithium diisopropyl amide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; 1,2-dimethoxyethane; ethanol; chloroform; water; acetic acid;

Reference yield:

: 1200498-30-1
(S)-tert-butyl 4-(5-bromo-2,4-difluorophenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-ylcarbamate

: 1200495-69-7
C₁₈H₁₈F₂N₄OS

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; water / 0.5 h / 70 °C / microwave

2: trifluoroacetic acid / chloroform / 3 h / 20 °C

With sodium carbonate; trifluoroacetic acid; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; chloroform; water;