di(1R,2S,5R)-menthyl phosphorochloridite

Base Information

• Chemical Name: di(1R,2S,5R)-menthyl phosphorochloridite
• CAS No.: 105449-76-1
• Molecular Formula: C₂₀H₃₈ClO₂P
• Molecular Weight: 376.947
• Mol file: 105449-76-1.mol

Synonyms:di(1R,2S,5R)-menthyl phosphorochloridite

Chemical Property of di(1R,2S,5R)-menthyl phosphorochloridite

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of di(1R,2S,5R)-menthyl phosphorochloridite

There total 2 articles about di(1R,2S,5R)-menthyl phosphorochloridite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(-)-menthol (2216-51-5) → di(1R,2S,5R)-menthyl phosphorochloridite (105449-76-1)

Guidance literature:

With triethylamine; phosphorus trichloride; In diethyl ether; for 2h; Ambient temperature;

DOI:10.1016/S0957-4166(99)00139-1

Reference yield:

(-)-menthol (2216-51-5) → di(1R,2S,5R)-menthyl phosphorochloridite (105449-76-1) + (1R,2S,5R)-(-)-menthyl phosphorodichloridite (95456-31-8)

Guidance literature:

With triethylamine; phosphorus trichloride; Inert atmosphere;

DOI:10.1002/ejic.200900304

Reference yield: 96.0%

(o-hydroxyphenyl)diphenylphosphine (60254-10-6) + di(1R,2S,5R)-menthyl phosphorochloridite (105449-76-1) → (1R,2S,5R)-(2-diphenylphosphanylphenoxy)-dimenthyloxyphosphane

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃;

DOI:10.1002/1615-4169(200209)344:8<868::AID-ADSC868>3.0.CO;2-M

upstream raw materials:

(-)-menthol

Downstream raw materials:

hydrogen di[(1R,2S,5R)-menthyl] phosphite