1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

Base Information

Chemical Name:1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone
CAS No.:1026087-38-6
Molecular Formula:C₂₅H₂₃F₉N₆O
Molecular Weight:594.483
Hs Code.:

Synonyms:1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

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Technology Process of 1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

There total 1 articles about 1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1026087-18-2
3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-carboxylic acid methoxyl-methyl-amide

: 931-50-0
cyclohexylmagnesium bromide

: 1026087-38-6
1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

Guidance literature:: 3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-carboxylic acid methoxyl-methyl-amide; cyclohexylmagnesium bromide; In tetrahydrofuran; at 0 ℃; for 0.5h;

With water; ammonium chloride; In tetrahydrofuran;

Reference yield:

: 1026087-38-6
1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

: (3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone oxime

Guidance literature:: With sodium hydroxide; hydroxylamine hydrochloride; In ethanol; at 20 - 70 ℃;

Reference yield:

: 1026087-38-6
1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone

: 74-88-4
methyl iodide

: 1026137-10-9
(3,5-bis-trifluoromethyl-benzyl)-[2-(cyclohexyl-methoxy-methyl)-5-trifluoromethyl-pyridin-3-ylmethyl]-(2-methyl-2H-tetrazol-5-yl)-amine

Guidance literature:: 1-(3-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-5-trifluoromethyl-pyridine-2-yl)-cyclohexyl-methanone; With sodium tetrahydroborate; In ethanol; at 0 ℃; for 0.5h;

With water; ammonium chloride; In ethanol;

methyl iodide; With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 0.166667h;