3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester

Base Information

• Chemical Name: 3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester
• CAS No.: 924650-12-4
• Molecular Formula: C₁₂H₁₄BrNO₄S
• Molecular Weight: 348.217
• Mol file: 924650-12-4.mol

Synonyms:3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester

Chemical Property of 3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester

There total 2 articles about 3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1,4-butanesultam (37441-50-2) + methyl 3-bromo-5-iodobenzoate (188813-07-2) → 3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester (924650-12-4)

Guidance literature:

With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 100 ℃; for 16h; Sealed tube;

Reference yield:

→ 3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester (924650-12-4)

Guidance literature:

Reference yield:

3-bromo-5-(1,1-dioxo-1λ6-[1,2]thiazinan-2-yl)-benzoic acid methyl ester (924650-12-4) + -butyl vinyl ether (111-34-2,92680-80-3) → C18H25NO5S

Guidance literature:

With 1,3-bis-(diphenylphosphino)propane; palladium diacetate; potassium carbonate; In water; N,N-dimethyl-formamide; Microwave irradiation;

DOI:10.1016/j.bmcl.2009.03.144

upstream raw materials:

1,4-butanesultam

methyl 3-bromo-5-iodobenzoate