188813-07-2

Basic information

• Product Name: Methyl 3-bromo-5-iodobenzoate
• Synonyms: 3-BroMo-5-iodobenzoic acid Methyl ester;Benzoic acid,3-broMo-5-iodo-, Methyl ester;Methyl 3-bromo-5-iodobenzoate 97%;Methyl3-bromo-5-iodobenzoate97%;Methyl 5-bromo-3-iodobenzoate;Benzoic acid, 3-bromo-5-iodo-, meth
• CAS NO: 188813-07-2
• Molecular Formula: C₈H₆BrIO₂
• Molecular Weight: 340.95
• Product Categories: Acids & Esters;Bromine Compounds;Iodine Compounds
• Mol File: 188813-07-2.mol

Chemical Properties

• Melting Point: 62.0-63.0 °C
• Boiling Point: 334.458 °C at 760 mmHg
• Flash Point: 156.075 °C
• Appearance: white crystal powder
• Density: 2.059 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: Methyl 3-bromo-5-iodobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3-bromo-5-iodobenzoate(188813-07-2)
• EPA Substance Registry System: Methyl 3-bromo-5-iodobenzoate(188813-07-2)

Safety Data

• Hazardous Substances Data: 188813-07-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 3-bromo-5-iodobenzoate is used as a building block for the synthesis of various biologically active molecules. Its unique structure allows for the creation of complex organic compounds with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical field, Methyl 3-bromo-5-iodobenzoate serves as a key intermediate in the synthesis of active ingredients for pesticides and other agrochemical products. Its presence in these compounds can enhance their effectiveness and selectivity.
Used in Research Laboratories:
Methyl 3-bromo-5-iodobenzoate is commonly used in research and development settings for the synthesis of complex organic compounds. Its versatility and reactivity make it a valuable tool for exploring new chemical reactions and pathways.
Used as a Reagent in Chemical Reactions:
Due to its unique structure, Methyl 3-bromo-5-iodobenzoate can be used as a reagent in various chemical reactions. It can facilitate the formation of new bonds and the transformation of other molecules, contributing to the advancement of organic chemistry.

InChI:InChI=1/C8H6BrIO2/c1-12-8(11)5-2-6(9)4-7(10)3-5/h2-4H,1H3

Upstream product

• 188815-32-9 3-bromo-5-iodo-benzoic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 188813-08-3 1-bromo-3-(hydroxymethyl)-5-iodobenzene 
• 1141486-82-9 C₁₈H₂₂BrNO₄ 
• 924650-24-8 methyl 3-bromo-5-(N-phenylmethan-10-ylsulfonamido)benzoate 
• 1244043-42-2 3-bromo-5-{4-[4-chlorophenyl(methyl)amino]benzoyl}benzoic acid methyl ester 
• 1150260-61-9 3-(5-chloropyridin-2-yl)-5-(1-hydroxy-1-methylethyl)-N-{(1R)-1-[1-oxido-6-(trifluoromethyl)pyridin-3-yl]ethyl}benzamide 
• 1150263-42-5 3-bromo-5-(5-chloro-pyridin-2-yl)-benzoic acid methyl ester 
• 1150263-45-8 methyl 3-(5-chloropyridin-2-yl)-5-isopropenylbenzoate 
• 1150263-50-5 3-(5-chloropyridin-2-yl)-5-(1-hydroxy-1-methylethyl)benzoic acid 
• 618-89-3 methyl 3-bromobenzoate 

Relevant articles and documents

On-Nanoparticle Gating Units Render an Ordinary Catalyst Substrate- And Site-Selective

When an organometallic catalyst is tethered onto a nanoparticle and is embedded in a monolayer of longer ligands terminated in "gating"end-groups, these groups can control the access and orientation of the incoming substrates. In this way, a nonspecific catalyst can become enzyme-like: it can select only certain substrates from substrate mixtures and, quite remarkably, can also preorganize these substrates such that only some of their otherwise equivalent sites react. For a simple, copper-based click reaction catalyst and for gating ligands terminated in charged groups, both substrate- and site-selectivities are on the order of 100, which is all the more notable given the relative simplicity of the on-particle monolayers compared to the intricacy of enzymes' active sites. The strategy of self-assembling macromolecular, on-nanoparticle environments to enhance selectivities of "ordinary"catalysts presented here is extendable to other types of catalysts and gating based on electrostatics, hydrophobicity, and chirality, or the combinations of these effects. Rational design of such systems should be guided by theoretical models we also describe.

BIS AROMATIC COMPOUNDS FOR USE AS LCT4 SYNTHASE INHIBITORS

There is provided compounds of formula I, wherein Y, ring A, Da, Db, D2, D3, L1, Y1, L2, Y2, L3 and Y3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.

BIS AROMATIC COMPOUNDS FOR USE AS LTC4 SYNTHASE INHIBITORS

There is provided compounds of formula (I), wherein Y, ring A1 D1, D2a, D2b, D3, L1, Y1, L3 and Y3 have meanings given in the description, and pharmaceutica

Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists

The present invention provides compounds and pharmaceutical compositions that act as antagonists at metabotropic glutamate receptors, and that are useful for treating neurological diseases and disorders. Methods of preparing the compounds also are disclosed.

META-GUANIDINE, UREA, THIOUREA OR AZACYCLIC AMINO BENZOIC ACID DERIVATIVES AS INTEGRIN ANTAGONISTS

The present invention relates to a class of compounds represented by the Formula Ior a pharmaceutically acceptable salt thereof, whereinA ispharmaceutical compositions thereof and methods of using such compounds and compositions as alphavbeta3 antagonists.