7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate

Base Information

• Chemical Name: 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate
• CAS No.: 1642785-09-8
• Molecular Formula: C₂₄H₁₇F₃O₇S
• Molecular Weight: 506.456
• Mol file: 1642785-09-8.mol

Synonyms:7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate

Chemical Property of 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate

There total 3 articles about 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.4%

trifluoromethylsulfonic anhydride (358-23-6) + 7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one (1610522-93-4) → 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate (1642785-09-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 12h;

DOI:10.1038/aps.2014.33

Reference yield:

ethyl 3-(3,4-bis(benzyloxy)phenyl)-3-oxopropanoate (1643318-41-5) → 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate (1642785-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 6 h / Reflux

2: triethylamine / dichloromethane / 12 h / 0 °C

With acetic acid; triethylamine; In dichloromethane;

DOI:10.1038/aps.2014.33

Reference yield:

1-(3,4-bis(benzyloxy)-2-hydroxyphenyl)ethanone (2652-27-9) → 7,8-bis(benzyloxy)-2-oxo-2H-chromen-4-yl trifluoromethanesulfonate (1642785-09-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium / 0.33 h / 120 °C

2: acetic acid / 6 h / Reflux

3: triethylamine / dichloromethane / 12 h / 0 °C

With sodium; acetic acid; triethylamine; In dichloromethane;

DOI:10.1038/aps.2014.33

upstream raw materials:

trifluoromethylsulfonic anhydride

7,8-bis(benzyloxy)-4-hydroxy-2H-chromen-2-one

ethyl 3-(3,4-bis(benzyloxy)phenyl)-3-oxopropanoate

1-(3,4-bis(benzyloxy)-2-hydroxyphenyl)ethanone

Downstream raw materials:

7,8-bis(benzyloxy)-4-(3-(benzyloxy)-4-methoxyphenyl)-2H-chromen-2-one

7,8-dihydroxy-4-(4-methoxyphenyl)-2H-chromen-2-one

7,8-dihydroxy-4-(3',4'-dimethoxyphenyl)-2H-1-chromen-2-one

7,8-dihydroxy-4-phenyl-2H-chromen-2-one