Technology Process of C22H19N3OS
There total 4 articles about C22H19N3OS which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetrakis(triphenylphosphine) palladium(0); triethylamine; copper(l) iodide / tetrahydrofuran / 192 h / 40 °C / Inert atmosphere
2: triethylamine; tetrabutyl ammonium fluoride / tetrahydrofuran / 48 h / 50 °C / Inert atmosphere
3: sodium hydrogencarbonate; magnesium sulfate; potassium permanganate / acetone; water / -10 °C
4: ammonium acetate / acetic acid / 115 °C
5: dipotassium peroxodisulfate / water; acetic acid / 20 °C
With
potassium permanganate; dipotassium peroxodisulfate; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); ammonium acetate; tetrabutyl ammonium fluoride; sodium hydrogencarbonate; magnesium sulfate; triethylamine;
In
tetrahydrofuran; water; acetic acid; acetone;
1: |Sonogashira Cross-Coupling;
DOI:10.1016/j.bmcl.2013.03.103
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydrogencarbonate; magnesium sulfate; potassium permanganate / acetone; water / -10 °C
2: ammonium acetate / acetic acid / 115 °C
3: dipotassium peroxodisulfate / water; acetic acid / 20 °C
With
potassium permanganate; dipotassium peroxodisulfate; ammonium acetate; sodium hydrogencarbonate; magnesium sulfate;
In
water; acetic acid; acetone;
DOI:10.1016/j.bmcl.2013.03.103