1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene

Base Information

• Chemical Name: 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene
• CAS No.: 1111628-58-0
• Molecular Formula: C₁₉H₃₀N₄O₄
• Molecular Weight: 378.472
• Mol file: 1111628-58-0.mol

Synonyms:1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene

Chemical Property of 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene

There total 2 articles about 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

4-amino-1-(N-ethylamino)benzene (5840-09-5) + tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate (145013-05-4) → 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene (1111628-58-0)

Guidance literature:

With triethylamine; mercury dichloride; In dichloromethane; at 0 - 20 ℃; for 15h;

DOI:10.1021/jm800838r

Reference yield: 72.0%

→ 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene (1111628-58-0)

Guidance literature:

Reference yield:

1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene (1111628-58-0) + trifluoroacetic acid (76-05-1) → 2C2HF3O2*C9H14N4

Guidance literature:

In dichloromethane; for 3h;

DOI:10.1021/jm800838r

upstream raw materials:

4-amino-1-(N-ethylamino)benzene

tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate