5840-09-5

Basic information

• Product Name: N-Ethyl-p-phenylenediamine
• Synonyms: N-Ethyl-1,4-benzenediamine;N-Ethyl-p-phenylenediamine;4-(EthylaMino)aniline 2HCl
• CAS NO: 5840-09-5
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• Mol File: 5840-09-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Ethyl-p-phenylenediamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ethyl-p-phenylenediamine(5840-09-5)
• EPA Substance Registry System: N-Ethyl-p-phenylenediamine(5840-09-5)

Safety Data

• Hazardous Substances Data: 5840-09-5(Hazardous Substances Data)

Upstream product

• 1222062-40-9 2-[(4-ethylaminophenylamino)methylene]malonic acid diethyl ester 
• 106-50-3 1,4-phenylenediamine 
• 100-01-6 4-nitro-aniline 
• 1826-56-8 N-ethyl-N-(4-nitrophenyl)acetamide 
• 529-65-7 N-ethylacetanilide 
• 612-64-6 N-ethyl-N-nitrosoaniline 
• 7647-01-0 hydrogenchloride 
• 19788-30-8 4-nitroso-N-ethylaniline 
• 945-81-3 N-nitroso N-ethyl-N-(4-nitroaniline) 

Downstream Products

• 1111628-58-0 1-[2,3-di(tert-butoxycarbonyl)guanidino]-4-(N-ethyl)benzene 
• 1111628-53-5 2-(4-ethylamino-phenylimino)-imidazolidine-1,3-dicarboxylic acid di-tert-butyl ester 
• 1615250-76-4 N-[1,3-di(tert-butoxycarbonyl)-4-(fur-2-yl)imidazolidin-2-ylidene]-4-ethylaminoaniline 
• 1615250-74-2 2-[(4-ethylaminophenyl)imino]-5-methyl-1,3-di(tert-butoxycarbonyl)imidazolidine 
• 1615250-69-5 1-[1-(tert-butoxycarbonyl)-3-phenylguanidino]-4-ethylaminobenzene 
• 1615250-67-3 1-[1-(tert-butoxycarbonyl)-3-(4-ethylaminophenyl)guanidino]ethyl acetate 
• 1615250-65-1 1-[1-(tert-butoxycarbonyl)-3-(furan-2-ylmethyl)guanidino]-4-ethylaminobenzene 
• 57838-84-3 N-[2-(4-Ethylamino-phenylamino)-5-hydroxy-4-methyl-phenyl]-acetamide 
• 56330-27-9 N-{6-[(Z)-4-Ethylamino-phenylimino]-4-methyl-3-oxo-cyclohexa-1,4-dienyl}-acetamide 

Relevant articles and documents

2,2-Bis(ethoxycarbonyl)vinyl (BECV) as a versatile amine protecting group for selective functional-group transformations

A 2,2-Bis(ethoxycarbonyl) vinyl- (BECV) group was used for the selective protection of amines at room temperature in the presence of potentially interfering functional groups such as OH, SH, COOH as well as other NH 2 groups. Several functional group transformations such as esterification, O-alkylation, O-acylation, N-alkylation, N-acylation, S-alkylation can selectively be carried out in the presence of the BECV group. The selective deprotection of the BECV group was achieved in a short time using ethylenediamine at room temperature while several other functional groups such as benzoate, aliphatic esters, amides and ethers remain intact. The BECV group shows orthogonal stability against the common protecting groups such as Fmoc, Cbz and Boc.

Guanidine and 2-aminoimidazoline aromatic derivatives as α2-adrenoceptor ligands: Searching for structure-activity relationships

In this paper, we report the synthesis of three new 2-aminoimidazoline (compounds 4b, 5b, and 6b) and three new guanidine derivatives (compounds 7b, 8b, and 9b) as potential α2-adrenoceptor antagonists for the treatment of depression. Their pha