1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

Base Information

Chemical Name:1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane
CAS No.:342023-68-1
Molecular Formula:C₃₀H₂₈IN₃O₂
Molecular Weight:589.476
Hs Code.:

Synonyms:1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

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Chemical Property of 1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

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Technology Process of 1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

There total 1 articles about 1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 342023-67-0
3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propan-1-ol

: 124-63-0
methanesulfonyl chloride

: 342023-68-1
1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

Guidance literature:: 3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propan-1-ol; methanesulfonyl chloride; With triethylamine; In ethyl acetate; at 0 ℃; for 0.5h;

With sodium iodide; In acetone; at 50 ℃; for 3h;

Reference yield: 92.0%

: 773837-37-9
sodium cyanide

: 342023-68-1
1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

: 342023-69-2
4-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl)-3-phenyl-1H-pyrazol-4-yl]butyronitrile

Guidance literature:: In dimethyl sulfoxide; at 60 ℃; for 2h;

Reference yield: 88.0%

: 342023-68-1
1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane

: 105-53-3
diethyl malonate

: 342023-70-5
diethyl 2-[3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propyl]malonate

Guidance literature:: diethyl malonate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h;

1-iodo-3-[1-[4-(5-methyl-2-phenyl-4-oxazolylmethoxy)benzyl]-3-phenyl-1H-pyrazol-4-yl]propane; In tetrahydrofuran; at 20 ℃; for 13h;