Technology Process of 5-chloro-3,4-dimethoxy-6-nitrobenzamide
There total 4 articles about 5-chloro-3,4-dimethoxy-6-nitrobenzamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydrogen carbonate, potassium carbonate / H2O / 0.33 h / 70 - 80 °C
2: 52 percent / nitric acid / 0.25 h / 0 - 10 °C
3: 92 percent / 10percent aq. potassium permanganate / acetone / Heating
4: 1.) thionyl chloride, 2.) NH3 liq. / 1.) reflux, 2.) liquid nitrogen
With
potassium permanganate; thionyl chloride; ammonia; nitric acid; sodium hydrogencarbonate; potassium carbonate;
In
water; acetone;
DOI:10.1071/CH9811561
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 52 percent / nitric acid / 0.25 h / 0 - 10 °C
2: 92 percent / 10percent aq. potassium permanganate / acetone / Heating
3: 1.) thionyl chloride, 2.) NH3 liq. / 1.) reflux, 2.) liquid nitrogen
With
potassium permanganate; thionyl chloride; ammonia; nitric acid;
In
acetone;
DOI:10.1071/CH9811561
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 92 percent / 10percent aq. potassium permanganate / acetone / Heating
2: 1.) thionyl chloride, 2.) NH3 liq. / 1.) reflux, 2.) liquid nitrogen
With
potassium permanganate; thionyl chloride; ammonia;
In
acetone;
DOI:10.1071/CH9811561
