2,3,6-Trifluoro-4-methoxypyridine

Base Information

Chemical Name:2,3,6-Trifluoro-4-methoxypyridine
CAS No.:858860-02-3
Molecular Formula:C6H4 F3 N O
Molecular Weight:163.1
Hs Code.:
DSSTox Substance ID:DTXSID10553976
Wikidata:Q72511550
Mol file:858860-02-3.mol

Synonyms:2,3,6-TRIFLUORO-4-METHOXYPYRIDINE;858860-02-3;4-methoxy-2,3,6-trifluoropyridine;Pyridine,2,3,6-trifluoro-4-methoxy-;SCHEMBL4374140;DTXSID10553976;AMY12513;AKOS006309959

Suppliers and Price of 2,3,6-Trifluoro-4-methoxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3,6-TRIFLUORO-4-METHOXYPYRIDINE 95.00%
5MG
$ 496.96

Alichem
4-Methoxy-2,3,6-trifluoropyridine
1g
$ 3097.65

Alichem
4-Methoxy-2,3,6-trifluoropyridine
500mg
$ 1786.10

Alichem
4-Methoxy-2,3,6-trifluoropyridine
250mg
$ 1009.40

Total 11 raw suppliers

Chemical Property of 2,3,6-Trifluoro-4-methoxypyridine

Chemical Property:

Boiling Point:155.9±35.0℃ (760 Torr)
Flash Point:48.1±25.9℃
PSA：22.12000
Density:1.367±0.06 g/cm3 (20 ºC 760 Torr)
LogP:1.50750
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:163.02449824
Heavy Atom Count:11
Complexity:135

Purity/Quality:

97% ^*data from raw suppliers

2,3,6-TRIFLUORO-4-METHOXYPYRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=NC(=C1F)F)F

Technology Process of 2,3,6-Trifluoro-4-methoxypyridine

There total 4 articles about 2,3,6-Trifluoro-4-methoxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 3-chloro-2,5,6-trifluoro-4-methoxypyridine

: 858860-02-3
2,3,6-trifluoro-4-methoxypyridine

Guidance literature:: With ammonium formate; palladium 10% on activated carbon; In methanol; at 50 ℃; for 10h;

Reference yield:

: 1735-84-8
3-chloro-2,4,5,6-tetrafluoropyridine

: 858860-02-3
2,3,6-trifluoro-4-methoxypyridine

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; tetrahydrofuran / 20 h / 0 - 20 °C

2: H₂; Et₃N / Pd-C / methanol / 24 h / 2280 Torr

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1016/j.bmcl.2005.04.007