2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime

Base Information

• Chemical Name: 2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime
• CAS No.: 158036-22-7
• Molecular Formula: C₁₂H₁₁NO₃
• Molecular Weight: 217.224
• Mol file: 158036-22-7.mol

Synonyms:2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime

Chemical Property of 2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime

There total 2 articles about 2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-bromophenyl)-oxoacetic acid methyl ester (122394-38-1) + trimethylsilylacetylene (1066-54-2) → 2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime (158036-22-7)

Guidance literature:

With nitrogen; triphenylphosphine; palladium diacetate; copper(I) iodide; In ethyl acetate; triethylamine;

Reference yield:

0-methylhydroxylamine hydrochloride + (2-bromophenyl)-oxoacetic acid methyl ester (122394-38-1) + trimethylsilylacetylene (1066-54-2) → 2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime (158036-22-7)

Guidance literature:

With nitrogen; triphenylphosphine; palladium diacetate; copper(I) iodide; In methanol; ethyl acetate; triethylamine;

Reference yield:

2-Ethynylphenylglyoxylic acid methyl ester-O-methyloxime (158036-22-7) + benzoyl chloride (98-88-4) → methyl 2-benzoyl-ethynylphenylglyoxylate O-methyloxime (158036-27-2)

Guidance literature:

With copper(II) chloride; triphenylphosphine; palladium diacetate; In diethyl ether; tert-butyl methyl ether; triethylamine;

upstream raw materials:

(2-bromophenyl)-oxoacetic acid methyl ester

trimethylsilylacetylene

Downstream raw materials:

methyl 2-benzoyl-ethynylphenylglyoxylate O-methyloxime

Methyl 2-(2-(3-chloro)thienylethynyl)-phenylglyoxylate O-methyloxime

2-ethynylphenylglyoxylic acid-N-methylamide-O-methyloxime

2[3-(2-Methylphenyl)-isoxazol-5-yl]-phenylglyoxylic acid methyl ester-O-methyloxime