N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine

Base Information

• Chemical Name: N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine
• CAS No.: 145389-77-1
• Molecular Formula: C₁₀H₁₄ClN₃O₅S₂
• Molecular Weight: 355.823
• Mol file: 145389-77-1.mol

Synonyms:N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine

Chemical Property of N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine

There total 1 articles about N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4-chloro-3-sulfamoylbenzenesulfonyl chloride (61450-06-4) + monoacetylaminoethylamine (1001-53-2) → N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine (145389-77-1)

Guidance literature:

With triethylamine; In acetone;

DOI:10.1021/jm00053a020

Reference yield: 64.0%

N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine (145389-77-1) → N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>ethylenediamine (145389-78-2)

Guidance literature:

With hydrogenchloride; In ethanol; for 32h; Heating;

DOI:10.1021/jm00053a020

Reference yield:

N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>-N'-acetylethylenediamine (145389-77-1) → 4-Chloro-benzene-1,3-disulfonic acid 3-amide 1-({2-[2-hydroxy-3-(naphthalen-1-yloxy)-propylamino]-ethyl}-amide)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / 6N HCl / ethanol / 32 h / Heating

2: 35 percent / ethanol / 30 h / Heating

With hydrogenchloride; In ethanol;

DOI:10.1021/jm00053a020

upstream raw materials:

4-chloro-3-sulfamoylbenzenesulfonyl chloride

monoacetylaminoethylamine

Downstream raw materials:

N-<(4-chloro-3-sulfamoylphenyl)sulfonyl>ethylenediamine