N-Acetylethylenediamine

Base Information

• Chemical Name: N-Acetylethylenediamine
• CAS No.: 1001-53-2
• Molecular Formula: C4H10N2O
• Molecular Weight: 102.136
• Hs Code.: 29241990
• Mol file: 1001-53-2.mol

Synonyms:N-(2-Aminoethyl)acetamide;Acetamide, N-(2-aminoethyl)- (8CI)(9CI);

Chemical Property of N-Acetylethylenediamine

Chemical Property:

• Appearance/Colour: White to yellow crystalline solid
• Vapor Pressure: 0.0021mmHg at 25°C
• Melting Point: 50 °C(lit.)
• Refractive Index: n20/D 1.485(lit.)
• Boiling Point: 290.24 °C at 760 mmHg
• PKA: 15.97±0.46(Predicted)
• Flash Point: 129.333 °C
• PSA: 55.12000
• Density: 0.98 g/cm³
• LogP: 0.17240
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Sensitive.: Hygroscopic
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(2-Aminoethyl)acetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R34:
• Hazard Codes: R34:
• Statements: 34
• Safety Statements: 23-24/25-36/37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: N-(2-Aminoethyl)acetamide may be used in the preparation of mixed two-component monolayers on glassy carbon. It may be used in the synthesis of lysidine.

Technology Process of N-Acetylethylenediamine

There total 27 articles about N-Acetylethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N-(2-azidoethyl)-acetamide (72200-24-9) → monoacetylaminoethylamine (1001-53-2)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; under 750.075 Torr;

DOI:10.1002/chem.201102772

Reference yield: 95.0%

acetic anhydride (108-24-7) + ethylenediamine (107-15-3,85404-18-8) → monoacetylaminoethylamine (1001-53-2)

Guidance literature:

With pyridine; aluminum oxide; at 68 - 69 ℃; for 0.25h; microwave irradiation;

DOI:10.1016/S0040-4039(02)00732-3

Reference yield: 83.5%

ethylenediamine (107-15-3,85404-18-8) → monoacetylaminoethylamine (1001-53-2) + N,N'-diacetylethylenediamine (871-78-3)

Guidance literature:

In tetrahydrofuran; at 25 ℃; for 14h; Inert atmosphere;

DOI:10.1021/cc900162w

upstream raw materials:

ethyl acetate

ethylenediamine

lysidine

acetic acid

Downstream raw materials:

N,N-bis(2-hydroxyethyl)ethylidenediamine

N-(2-acetylamino-ethyl)-N'-nitro-guanidine

lysidine

N-(2-acetylaminoethyl)-N'-phenylurea

Refernces

• 1、 Morisaki,Bloch. "". . p. 309,310. Retrieved 1972.
• 2、 Hu, Peng,Ben-David, Yehoshoa,Milstein, David. "Rechargeable hydrogen storage system based on the dehydrogenative coupling of ethylenediamine with ethanol". . p. 1061 - 1064. Retrieved 2016.
• 3、 Baranov, Vladimir V.,Antonova, Maria M.,Karnoukhova, Valentina A.,Kravchenko, Angelina N.. "Unusual formation of imidazooxazolone in the reaction of 1-[(2-acetylamino)ethyl]imidazolone with KSCN in the presence of AcOH". . p. 63 - 72. Retrieved 2017.
• 4、 Gitis, K. M.,Raevskaya, N. I.,Isagulyants, G. V.. "THE STAGED SYNTHESIS OF 2-METHYLIMIDAZOLE FROM ETHYLENEDIAMINE AND ACETIC ACID IN THE PRESENCE OF A BIFUNCTIONAL ALUMINOPLATINUM CATALYST". . p. 1551 - 1554. Retrieved 1992.
• 5、 Baranov, Vladimir V.,Antonova, Maria M.,Karnoukhova, Valentina A.,Kravchenko, Angelina N.. "Unusual formation of imidazooxazolone in the reaction of 1-[(2-Acetylamino)ethyl]imidazolone with KSCN in the presence of AcOH". . p. 63 - 72. Retrieved 2017/04/14.