methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate

Base Information

Chemical Name:methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate
CAS No.:1032010-93-7
Molecular Formula:C₁₅H₁₅N₃O₃
Molecular Weight:285.302
Hs Code.:

Synonyms:methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate

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Technology Process of methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate

There total 1 articles about methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 100-52-7
benzaldehyde

: 108-26-9
3-methyl-2-pyrazoline-5-one

: 105-34-0
methyl 2-cyanoacetate

: 1032010-93-7
methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate

Guidance literature:: With methanol; sodium acetate; at 20 ℃; for 1h; Green chemistry;
DOI:10.1016/j.crci.2013.03.003

Reference yield: 69.0%

: 1032010-93-7
methyl 2-cyano-3-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-3-phenylpropanoate

: methyl (1S*,2R*,3R*)-1-cyano-4-methyl-7-oxo-2-phenyl-5,6-diazaspiro[2.4]-hept-4-ene-1-carboxylate

Guidance literature:: With bromine; sodium ethanolate; In ethanol; at 20 ℃; for 3h; Reagent/catalyst; Solvent; Temperature;
DOI:10.1016/j.mencom.2016.01.008