(+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide)

Base Information

• Chemical Name: (+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide)
• CAS No.: 1156406-05-1
• Molecular Formula: C₄₀H₃₂O₄P₂
• Molecular Weight: 638.639
• Mol file: 1156406-05-1.mol

Synonyms:(+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide)

Chemical Property of (+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide)

There total 2 articles about (+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

6-diphenylphosphinyl-2,3-dihydrobenzofuran (1156406-03-9) → (+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide) (1156406-05-1)

Guidance literature:

6-diphenylphosphinyl-2,3-dihydrobenzofuran; With tert.-butyl lithium; In tetrahydrofuran; pentane; at -80 ℃; for 3h; Inert atmosphere;

With iron(III) chloride; In tetrahydrofuran; pentane; at 20 ℃; for 13h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.02.182

Reference yield:

C16H12Cl4O4P2 + phenylmagnesium bromide (100-58-3) → (+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide) (1156406-05-1)

Guidance literature:

In tetrahydrofuran; N,N-dimethyl-formamide; at -80 - 20 ℃; for 18h; Inert atmosphere;

DOI:10.1016/j.tet.2018.05.062

Reference yield: 53.0%

(+/-)-(2,2',3,3'-tetrahydro-[7,7'-bibenzofuran]-6,6'-diyl)bis(diphenylphosphine oxide) (1156406-05-1) → BICMAP (1157852-82-8,1157852-83-9,1156405-95-6)

Guidance literature:

With trichlorosilane; triethylamine; In m-xylene; at 110 ℃; for 6h; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.02.182

upstream raw materials:

6-diphenylphosphinyl-2,3-dihydrobenzofuran

phenylmagnesium bromide

Downstream raw materials:

BICMAP