dibenzyl ethylphosphonate

Base Information

• Chemical Name: dibenzyl ethylphosphonate
• CAS No.: 4537-62-6
• Molecular Formula: C₁₆H₁₉O₃P
• Molecular Weight: 290.299
• Mol file: 4537-62-6.mol

Synonyms:dibenzyl ethylphosphonate

Chemical Property of dibenzyl ethylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dibenzyl ethylphosphonate

There total 7 articles about dibenzyl ethylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

ethylphosphonic acid (6779-09-5) + benzyl alcohol (100-51-6,185532-71-2) → dibenzyl ethylphosphonate (4537-62-6)

Guidance literature:

With p-TsOH-Celite; at 20 ℃;

DOI:10.3184/030823407X218066

Reference yield: 68.0%

Ethylphosphonic dichloride (1066-50-8) + benzyl alcohol (100-51-6,185532-71-2) → dibenzyl ethylphosphonate (4537-62-6)

Guidance literature:

With aluminum oxide; at 20 ℃;

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → dibenzyl ethylphosphonate (4537-62-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diisopropyl ethylamine, 1H-tetrazole / benzene / 4 - 20 °C

2: diisopropyl ethylamine / benzene / Ambient temperature

With 1H-tetrazole; N-ethyl-N,N-diisopropylamine; In benzene;

DOI:10.1016/S0040-4039(97)10421-X

upstream raw materials:

ethylphosphonic acid diethyl ester

benzyl chloride

diethyl benzylphosphonate

dibenzyl L-glutamate

Downstream raw materials:

2,3,5-tri-O-benzyl-α-D-ribofuranosyl benzyl ethylphosphonate

ethyl-phosphonic acid benzyl ester-diethylamide