6779-09-5

Basic information

• Product Name: ETHYLPHOSPHONIC ACID
• Synonyms: ETHANEPHOSPHONIC ACID;ETHYLPHOSPHONIC ACID;ETHYLPHOSPHONIC ACID, 98+%;Ethanephosphonic acid, 98+%;Ethyl-phosphonate;4-Ethylphosphonic Acid;Ethylphosphonic acid Solution, 100ppm
• CAS NO: 6779-09-5
• Molecular Formula: C2H7O3P
• Molecular Weight: 110.05
• EINECS: 229-839-2
• Product Categories: Organic Building Blocks;Phosphonic/Phosphinic Acids;Phosphorus Compounds
• Mol File: 6779-09-5.mol
• Article Data: 6

Chemical Properties

• Melting Point: 61-63 °C(lit.)
• Boiling Point: 330-340℃ (8 Torr)
• Flash Point: 111.3°C
• Appearance: white crystalline powder
• Vapor Pressure: 0.00365mmHg at 25°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: pK1:2.43;pK2:8.05 (25°C)
• Water Solubility: Soluble in water.
• Sensitive: Moisture Sensitive
• Stability: Stable. Incompatible with strong oxidizing agents, strong bases.
• BRN: 1743032
• CAS DataBase Reference: ETHYLPHOSPHONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYLPHOSPHONIC ACID(6779-09-5)
• EPA Substance Registry System: ETHYLPHOSPHONIC ACID(6779-09-5)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-28-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 6779-09-5(Hazardous Substances Data)

Usage

Chemical Properties

white crystalline powder

Uses

Ethylphosphonic acid is used as an internal standard in the determination of fosfomycin in human plasma. It is also used in the synthesis of nucleotide analogs.

General Description

The synthesis of novel nucleotide analogs based on phosphonic acids from ethylphosphonic acid was studied.

InChI:InChI=1/C2H7O3P/c1-2-6(3,4)5/h2H2,1H3,(H2,3,4,5)/p-2

Upstream product

• 78-38-6 ethylphosphonic acid diethyl ester 
• 2404-58-2 dibutyl ethylphosphonate 
• 27353-75-9 Chlor(diethylamino)ethylphosphan 
• 13237-78-0 2.4-Dioxo-2-aethyl-4H-1.3.2-benzodioxaphosphorin 
• 74-96-4 ethyl bromide 
• 64-17-5 ethanol 
• 124-38-9 carbon dioxide 
• 7647-01-0 hydrogenchloride 
• 12185-10-3 phosphorous 
• 593-68-0 ethyl phosphine 
• 74-85-1 ethene 
• 1066-50-8 Ethylphosphonic dichloride 
• 7732-18-5 water 
• 44494-01-1 tetrachloroethylphosphorane 

Downstream Products

• 22987-21-9 β-Hydroxyethanphosphonsaeure 
• 6163-76-4 di-n-propyl ethylphosphonate 
• 1066-50-8 Ethylphosphonic dichloride 
• 78-38-6 ethylphosphonic acid diethyl ester 
• 2404-58-2 dibutyl ethylphosphonate 
• 1929-44-8 monobutyl ethylphosphonate 
• 20442-53-9 monopropyl ethylphosphonate 
• 7305-61-5 ethyl hydrogen ethylphosphonate 
• 6163-82-2 O,O'-dipentyl ethylphosphonate 
• 96679-89-9 Mo(CO)4{(P(C₆H₅)2O)2P(O)C₂H₅} 
• 151299-67-1 C₆H₁₅O₃P 
• 145007-52-9 T3P 
• 4537-62-6 dibenzyl ethylphosphonate 
• 74-84-0 ethane 

Relevant articles and documents

Mixtures of dialkylphosphinic acids and alkylphosphinic acids, a process for preparation thereof and use thereof

The invention relates to mixtures of at least one dialkylphosphinic acid of the formula (I) in which R1, R2 are the same or different and are each independently C1-C18-alkyl, C2-C18-alkenyl, C6-C18-aryl, C7-C18-alkylaryl, with at least one alkylphosphonic acid of the formula (II) in which R3 is C1-C18-alkyl, C2-C18-alkenyl, C6-C18-aryl or C7-C18-alkylaryl; to a process for preparation thereof and to the use thereof.

Dealkylation of dialkyl phosphonates with boron tribromide

Boron tribromide cleanly and quantitatively converts dimethyl-, diethyl-, diisopropyl-, and ditertiobutyl phosphonates RP(O)(OR')2 into the corresponding phosphonic acids RP(O)(OH)2 via methanolysis. The use of boron tribromide is compatible with a variety of functionalities in the R group.

Synergistic herbicidal compositions

Synergistic herbicidal activity is displayed by compositions comprising the following two components: (a) a pyrrolidone of the formula STR1 in which X is selected from the group consisting of hydrogen, chlorine and methyl; Y is selected from the group consisting of hydrogen, chlorine and bromine; Z is selected from the group consisting of chlorine and bromine; R1 is selected from the group consisting of hydrogen and C1 -C4 alkyl; R2 is selected from the group consisting of hydrogen, halogen, C1 -C4 alkyl, acetyl, trifluoromethyl, nitro, cyano, C1 -C4 alkoxy, C1 -C4 alkylthio, C1 -C4 alkylsulfinyl, C1 -C4 alkylsulfonyl, trifluoromethylsulfinyl, trifluoromethylsulfonyl, pentafluoropropionamido, and 3-methylureido; and R3 is selected from the group consisting of hydrogen, C1 -C4 alkyl, chlorine and trifluoromethyl; and (b) a phosphonic acid of the formula STR2 in which R4 is selected from the group consisting of C1 -C4 alkyl, C1 -C4 haloalkyl, and --CH2 NHCH2 COOH, at a weight ratio of (a) to (b) of from about 0.1:1 to about 20:1.