1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

Base Information

Chemical Name:1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate
CAS No.:852880-79-6
Molecular Formula:C₃₁H₃₇Cl₂FN₂O₇
Molecular Weight:639.548
Hs Code.:

1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

Synonyms:1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

Suppliers and Price of 1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

There total 1 articles about 1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 644982-86-5
1-piperidinecarboxylic acid, 4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-4-(4-fluorophenyl)-1,1-dimethyl ester

: 852880-78-5
glycine ethyl ester hydrochloride

: 852880-79-6
1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

Guidance literature:: 1-piperidinecarboxylic acid, 4-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-4-(4-fluorophenyl)-1,1-dimethyl ester; glycine ethyl ester hydrochloride; In DMF (N,N-dimethyl-formamide); at 20 - 55 ℃; for 2.5 - 3.75h;

With potassium carbonate; dimethyl sulfate; In DMF (N,N-dimethyl-formamide); at 20 ℃;

Reference yield:

: 852880-79-6
1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate

: 852880-80-9
1-[(3,5-dichlorophenyl)methyl]-3-[4-(4-fluorophenyl)-4-piperidinyl]-2,4-pyrrolidinedione; hydrochloride salt

Guidance literature:: 1,1-dimethylethyl 4-{2-{[(3,5-dichlorophenyl)-methyl]-[2-(ethyloxy)-2-oxoethyl]-amino}-1-[(methyloxy)-carbonyl]-2-oxoethyl}-4-(4-fluorophenyl)-1-piperidinecarboxylate; In ethanol; tert-butyl methyl ether; at 30 ℃;

With sodium ethanolate; In ethanol; tert-butyl methyl ether; at 0 - 5 ℃; for 0.333333 - 0.666667h;

With hydrogenchloride; water; In tetrahydrofuran; ethanol; tert-butyl methyl ether; at 20 - 106 ℃; pH=1 - 3; Heating / reflux;