P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene

Base Information

• Chemical Name: P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene
• CAS No.: 252202-13-4
• Molecular Formula: C₃₁H₂₇OP
• Molecular Weight: 446.529
• Mol file: 252202-13-4.mol

Synonyms:P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene

Chemical Property of P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene

There total 3 articles about P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Diphenylphosphine oxide (4559-70-0) + P-1-(4',6'-dimethyl-2'-trifluoromethylsulfonyloxyphenyl)-2-methylnaphthalene (252202-12-3) → P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene (252202-13-4)

Guidance literature:

With palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In dimethyl sulfoxide; at 100 ℃; for 6h;

DOI:10.1016/S0957-4166(99)00299-2

Reference yield:

P-1-(4',6'-dimethyl-2'-hydroxyphenyl)-2-methylnaphthalene (252202-11-2) → P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene (252202-13-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / DABCO / CH₂Cl₂ / 0.5 h / 0 °C

2: 86 percent / Pd(OAc)2; dppb; (iPr)2NEt / dimethylsulfoxide / 6 h / 100 °C

With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In dichloromethane; dimethyl sulfoxide; 1: triflation / 2: Substitution;

DOI:10.1016/S0957-4166(99)00299-2

Reference yield:

2-(2-bromomethyl-naphthalen-1-yl)-3,5-dimethyl-phenol → P-1-(4',6'-dimethyl-2'-diphenylphosphanylphenyl)-2-methylnaphthalene (252202-13-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / LiAlH₄ / diethyl ether / 1 h / 20 °C

2: 98 percent / DABCO / CH₂Cl₂ / 0.5 h / 0 °C

3: 86 percent / Pd(OAc)2; dppb; (iPr)2NEt / dimethylsulfoxide / 6 h / 100 °C

With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate; lithium aluminium tetrahydride; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In diethyl ether; dichloromethane; dimethyl sulfoxide; 1: Reduction / 2: triflation / 3: Substitution;

DOI:10.1016/S0957-4166(99)00299-2

upstream raw materials:

Diphenylphosphine oxide

P-1-(4',6'-dimethyl-2'-trifluoromethylsulfonyloxyphenyl)-2-methylnaphthalene

P-1-(4',6'-dimethyl-2'-hydroxyphenyl)-2-methylnaphthalene