C₃₉H₅₄O₈Si₂

Base Information

• Chemical Name: C₃₉H₅₄O₈Si₂
• CAS No.: 1313275-00-1
• Molecular Formula: C₃₉H₅₄O₈Si₂
• Molecular Weight: 707.024
• Mol file: 1313275-00-1.mol

Synonyms:C₃₉H₅₄O₈Si₂

Chemical Property of C₃₉H₅₄O₈Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₅₄O₈Si₂

There total 30 articles about C₃₉H₅₄O₈Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

Di-tert-butyldichlorosilane (18395-90-9) + C31H38O8Si (1313275-61-4) → C39H54O8Si2 (1313275-00-1)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 23 - 55 ℃; for 1.33333h;

Reference yield:

(2S)-2-(tert-butyldimethylsilyloxy)-4-hydroxy-N-methoxy-N-methylbutanamide (1313275-47-6) → C39H54O8Si2 (1313275-00-1)

Guidance literature:

Multi-step reaction with 9 steps

1.1: sodium hydrogencarbonate; sodium hypochlorite / potassium bromide; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane; water / 0.25 h / 23 °C

2.1: C₁₃H₁₈NO₂^(1-)*Li⁽¹⁺⁾ / toluene; hexane / 1.33 h / 0 °C / Inert atmosphere

2.2: 6 h / -70 - 10 °C

3.1: scandium tris(trifluoromethanesulfonate) / dichloromethane / 0.5 h / 23 °C

4.1: tetrahydrofuran / 2 h / 0 °C

5.1: Hoveyda-Grubbs catalyst second generation / benzene / 0.67 h / 23 °C / Inert atmosphere; Heating

6.1: lithium tert-butoxide / tetrahydrofuran / 0.08 h / -78 °C

6.2: 2.5 h / -78 - -22 °C

6.3: 4.5 h / -22 - 23 °C

7.1: 2,6-dimethylpyridine; sodium periodate; potassium osmate(VI) dihydrate / water; tetrahydrofuran / 2 h / 0 - 23 °C

8.1: bromocatecholborane / dichloromethane / 0.75 h / -78 °C

8.2: -78 - 23 °C

9.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol / N,N-dimethyl-formamide / 1.33 h / 23 - 55 °C

With 2,6-dimethylpyridine; C₁₃H₁₈NO₂^(1-)*Li⁽¹⁺⁾; potassium osmate(VI) dihydrate; sodium hypochlorite; sodium periodate; bromocatecholborane; sodium hydrogencarbonate; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; Hoveyda-Grubbs catalyst second generation; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene; benzene;

Reference yield:

(2S,4S)-2-(tert-butyldimethylsilyloxy)-4-hydroxy-N-methoxy-N-methylhex-5-enamide (1335208-31-5) → C39H54O8Si2 (1313275-00-1)

Guidance literature:

Multi-step reaction with 7 steps

1.1: scandium tris(trifluoromethanesulfonate) / dichloromethane / 0.5 h / 23 °C

2.1: tetrahydrofuran / 2 h / 0 °C

3.1: Hoveyda-Grubbs catalyst second generation / benzene / 0.67 h / 23 °C / Inert atmosphere; Heating

4.1: lithium tert-butoxide / tetrahydrofuran / 0.08 h / -78 °C

4.2: 2.5 h / -78 - -22 °C

4.3: 4.5 h / -22 - 23 °C

5.1: 2,6-dimethylpyridine; sodium periodate; potassium osmate(VI) dihydrate / water; tetrahydrofuran / 2 h / 0 - 23 °C

6.1: bromocatecholborane / dichloromethane / 0.75 h / -78 °C

6.2: -78 - 23 °C

7.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol / N,N-dimethyl-formamide / 1.33 h / 23 - 55 °C

With 2,6-dimethylpyridine; potassium osmate(VI) dihydrate; sodium periodate; bromocatecholborane; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; lithium tert-butoxide; Hoveyda-Grubbs catalyst second generation; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; benzene;

upstream raw materials:

tert-butyldimethylsilyl chloride

2-hydroxy-p-toluic acid

methyl 2-hydroxy-4-methylbenzoate

(3S)-3-[(1,1-Dimethylethyl)dimethylsilyloxy]-oxolan-2-one

Downstream raw materials:

C₄₇H₆₄O₁₃Si₂

C₄₇H₆₄O₁₃Si₂

C₄₇H₆₄O₁₃Si₂

KCN-Triox₁