C₁₂H₁₄F₃NO₂

Base Information

Chemical Name:C₁₂H₁₄F₃NO₂
CAS No.:1445796-43-9
Molecular Formula:C₁₂H₁₄F₃NO₂
Molecular Weight:261.244
Hs Code.:

C<sub>12</sub>H<sub>14</sub>F<sub>3</sub>NO<sub>2</sub>

Synonyms:C₁₂H₁₄F₃NO₂

Suppliers and Price of C₁₂H₁₄F₃NO₂

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₁₂H₁₄F₃NO₂

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₁₂H₁₄F₃NO₂

There total 6 articles about C₁₂H₁₄F₃NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1445796-42-8
C₁₂H₁₅F₂NO₃

: 1445796-43-9
C₁₂H₁₄F₃NO₂

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at -78 - 20 ℃; for 2h; Inert atmosphere;

Reference yield:

: 2646-91-5
2,3-difluorobenzaldehyde

: 1445796-43-9
C₁₂H₁₄F₃NO₂

Guidance literature:: Multi-step reaction with 6 steps

1: N-Bromosuccinimide; sulfuric acid / 4 h / 60 °C / Inert atmosphere

2: sodium tetrahydroborate / methanol / 2.5 h / 0 - 20 °C

3: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C

4: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / 1,4-dioxane / 100 °C

5: sodium tetrahydroborate / tetrahydrofuran / 20 °C

6: diethylamino-sulfur trifluoride / dichloromethane / 2 h / -78 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-Bromosuccinimide; diethylamino-sulfur trifluoride; sulfuric acid; caesium carbonate; triethylamine; XPhos; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;

Reference yield:

: 887585-71-9
(5-bromo-2,3-difluorophenyl)methanol

: 1445796-43-9
C₁₂H₁₄F₃NO₂

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / tetrahydrofuran / 2 h / 0 - 20 °C

2: caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; XPhos / 1,4-dioxane / 100 °C

3: sodium tetrahydroborate / tetrahydrofuran / 20 °C

4: diethylamino-sulfur trifluoride / dichloromethane / 2 h / -78 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; diethylamino-sulfur trifluoride; caesium carbonate; triethylamine; XPhos; In tetrahydrofuran; 1,4-dioxane; dichloromethane;