C₂₄H₃₀N₈O₉S₄

Base Information

• Chemical Name: C₂₄H₃₀N₈O₉S₄
• CAS No.: 884335-06-2
• Molecular Formula: C₂₄H₃₀N₈O₉S₄
• Molecular Weight: 702.814
• Mol file: 884335-06-2.mol

Synonyms:C₂₄H₃₀N₈O₉S₄

Chemical Property of C₂₄H₃₀N₈O₉S₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₄H₃₀N₈O₉S₄

There total 9 articles about C₂₄H₃₀N₈O₉S₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

N-[1-[(Z)-4-((4R,5R)-5-Azido-2,2-dioxo-2λ6-[1,2,3]oxathiazinan-4-yl)-but-3-enylamino]-1-methylsulfanyl-meth-(Z)-ylidene]-4-methoxy-benzenesulfonamide (884335-05-1) + [(4-methoxyphenyl)sulfonyl]carbonimidic dichloride (81066-76-4) → C24H30N8O9S4 (884335-06-2)

Guidance literature:

N-[1-[(Z)-4-((4R,5R)-5-Azido-2,2-dioxo-2λ⁶-[1,2,3]oxathiazinan-4-yl)-but-3-enylamino]-1-methylsulfanyl-meth-(Z)-ylidene]-4-methoxy-benzenesulfonamide; [(4-methoxyphenyl)sulfonyl]carbonimidic dichloride; With potassium tert-butylate;

With 1,1,1,3,3,3-hexamethyl-disilazane;

DOI:10.1021/ja0608545

Reference yield:

Toluene-4-sulfonic acid 4-((4R,5S)-5-hydroxy-2,2-dioxo-2λ6-[1,2,3]oxathiazinan-4-yl)-but-3-ynyl ester (884335-03-9) → C24H30N8O9S4 (884335-06-2)

Guidance literature:

Multi-step reaction with 9 steps

1.1: H₂ / Pd/CaCO₃/Pb / tetrahydrofuran

2.1: NaN₃; nBu₄NI / dimethylformamide

3.1: 85 percent / nBu₄NI; K₂CO₃ / acetonitrile

4.1: Me₃P; H₂O / tetrahydrofuran

5.1: iPr₂NEt / acetonitrile

6.1: pyridine; DMAP / CH₂Cl₂

7.1: NaN₃ / dimethylformamide / -15 °C

8.1: 74 percent / (NH₄)2Ce(NO₃)6 / CH₂Cl₂; 2-methyl-propan-2-ol

9.1: tBuOK

9.2: 70 percent / (Me₃Si)2NH

With pyridine; dmap; sodium azide; ammonium cerium(IV) nitrate; potassium tert-butylate; water; hydrogen; tetra-(n-butyl)ammonium iodide; potassium carbonate; N-ethyl-N,N-diisopropylamine; trimethylphosphane; Lindlar's catalyst; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1021/ja0608545

Reference yield:

(4R,5S)-4-((Z)-4-Azido-but-1-enyl)-2,2-dioxo-2λ6-[1,2,3]oxathiazinan-5-ol (884335-17-5) → C24H30N8O9S4 (884335-06-2)

Guidance literature:

Multi-step reaction with 7 steps

1.1: 85 percent / nBu₄NI; K₂CO₃ / acetonitrile

2.1: Me₃P; H₂O / tetrahydrofuran

3.1: iPr₂NEt / acetonitrile

4.1: pyridine; DMAP / CH₂Cl₂

5.1: NaN₃ / dimethylformamide / -15 °C

6.1: 74 percent / (NH₄)2Ce(NO₃)6 / CH₂Cl₂; 2-methyl-propan-2-ol

7.1: tBuOK

7.2: 70 percent / (Me₃Si)2NH

With pyridine; dmap; sodium azide; ammonium cerium(IV) nitrate; potassium tert-butylate; water; tetra-(n-butyl)ammonium iodide; potassium carbonate; N-ethyl-N,N-diisopropylamine; trimethylphosphane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;

DOI:10.1021/ja0608545

upstream raw materials:

N-[1-[(Z)-4-((4R,5R)-5-Azido-2,2-dioxo-2λ⁶-[1,2,3]oxathiazinan-4-yl)-but-3-enylamino]-1-methylsulfanyl-meth-(Z)-ylidene]-4-methoxy-benzenesulfonamide

[(4-methoxyphenyl)sulfonyl]carbonimidic dichloride

(4R,5S)-4-((Z)-4-Azido-but-1-enyl)-2,2-dioxo-2λ⁶-[1,2,3]oxathiazinan-5-ol

Toluene-4-sulfonic acid (Z)-4-((4R,5S)-5-hydroxy-2,2-dioxo-2λ⁶-[1,2,3]oxathiazinan-4-yl)-but-3-enyl ester

Downstream raw materials:

C₂₃H₃₀N₆O₇S₂

C₂₄H₃₄N₆O₇S₃

Carbamic acid (Z)-(4R,5R)-5-({amino-[(E)-4-methoxy-benzenesulfonylimino]-methyl}-amino)-2-[(Z)-4-methoxy-benzenesulfonylimino]-2,3,4,5,8,9-hexahydro-1H-[1,3]diazonin-4-ylmethyl ester

Carbamic acid (3R,4S,4aR,5S)-4-({amino-[(E)-4-methoxy-benzenesulfonylimino]-methyl}-amino)-4a,5-dihydroxy-1-[(E)-4-methoxy-benzenesulfonylimino]-octahydro-pyrrolo[1,2-c]pyrimidin-3-ylmethyl ester