1-(prop-2-ynyloxy)-4-vinylbenzene

Base Information

• Chemical Name: 1-(prop-2-ynyloxy)-4-vinylbenzene
• CAS No.: 69678-76-8
• Molecular Formula: C₁₁H₁₀O
• Molecular Weight: 158.2
• Mol file: 69678-76-8.mol

Synonyms:1-(prop-2-ynyloxy)-4-vinylbenzene

Chemical Property of 1-(prop-2-ynyloxy)-4-vinylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(prop-2-ynyloxy)-4-vinylbenzene

There total 2 articles about 1-(prop-2-ynyloxy)-4-vinylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

4-Vinylphenol (2628-17-3,24979-70-2) + propargyl bromide (106-96-7) → 1-(prop-2-ynyloxy)-4-vinylbenzene (69678-76-8)

Guidance literature:

4-Vinylphenol; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

propargyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.1039/d0cc00336k

Reference yield:

p-acetoxystyrene (2628-16-2) → 1-(prop-2-ynyloxy)-4-vinylbenzene (69678-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide / water / 4 h / 0 °C

2.1: potassium carbonate / N,N-dimethyl-formamide / 0.08 h / 20 °C

2.2: 48 h / 20 °C

With potassium carbonate; potassium hydroxide; In water; N,N-dimethyl-formamide;

DOI:10.1039/d0cc00336k

Reference yield: 89.0%

1-(prop-2-ynyloxy)-4-vinylbenzene (69678-76-8) + (trifluoromethyl)trimethylsilane (81290-20-2) → 1-(2,2-difluorocyclopropyl)-4-(prop-2-yn-1-yloxy)benzene

Guidance literature:

With sodium iodide; In tetrahydrofuran; at 65 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c03268

upstream raw materials:

4-Vinylphenol

propargyl bromide

p-acetoxystyrene

Downstream raw materials:

C₁₁H₉O^(1-)*Ag⁽¹⁺⁾