C₅₅H₈₂N₂O₃SSi

Base Information

• Chemical Name: C₅₅H₈₂N₂O₃SSi
• CAS No.: 241816-40-0
• Molecular Formula: C₅₅H₈₂N₂O₃SSi
• Molecular Weight: 879.419
• Mol file: 241816-40-0.mol

Synonyms:C₅₅H₈₂N₂O₃SSi

Chemical Property of C₅₅H₈₂N₂O₃SSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₅H₈₂N₂O₃SSi

There total 7 articles about C₅₅H₈₂N₂O₃SSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

trisylhydrazine (39085-59-1) + 1-[(3S,5R,8R,9R,10R,13R,14R,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethanone (241816-36-4) → C55H82N2O3SSi (241816-40-0)

Guidance literature:

With hydrogenchloride; In acetonitrile; for 0.5h; Ambient temperature;

DOI:10.1016/S0960-894X(99)00220-6

Reference yield:

20-ξ(2)-Hydroxy-3-oxo-dammaren-(24); Dipterocarpol (19222-66-3) → C55H82N2O3SSi (241816-40-0)

Guidance literature:

Multi-step reaction with 7 steps

1: 24 percent / NaBH₄ / propan-2-ol / 3.5 h / Ambient temperature

2: 95 percent / H₂ / Pd/C / ethanol / 3 h

3: 2.) O₃, Ph₃P / 1.) DMSO, 190 deg C, 3 h, 2.) CH₂Cl₂, MeOH

4: 87 percent / imidazole / acetonitrile / 12 h / 60 °C

5: 72 percent / pTsOH / 7.5 h / Heating

6: 1.) MeLi, 2.) methyl salicylate / 1.) Et₂O, 0 deg C, 30 min, 2.) Et₂O, -78 deg C, 40 min

7: 94 percent / aq. HCl / acetonitrile / 0.5 h / Ambient temperature

With 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; methyllithium; hydrogen; toluene-4-sulfonic acid; ozone; triphenylphosphine; methyl salicylate; palladium on activated charcoal; In ethanol; isopropyl alcohol; acetonitrile;

DOI:10.1016/S0960-894X(99)00220-6

Reference yield:

'Dammarendiol' (19132-83-3) → C55H82N2O3SSi (241816-40-0)

Guidance literature:

Multi-step reaction with 6 steps

1: 95 percent / H₂ / Pd/C / ethanol / 3 h

2: 2.) O₃, Ph₃P / 1.) DMSO, 190 deg C, 3 h, 2.) CH₂Cl₂, MeOH

3: 87 percent / imidazole / acetonitrile / 12 h / 60 °C

4: 72 percent / pTsOH / 7.5 h / Heating

5: 1.) MeLi, 2.) methyl salicylate / 1.) Et₂O, 0 deg C, 30 min, 2.) Et₂O, -78 deg C, 40 min

6: 94 percent / aq. HCl / acetonitrile / 0.5 h / Ambient temperature

With 1H-imidazole; hydrogenchloride; methyllithium; hydrogen; toluene-4-sulfonic acid; ozone; triphenylphosphine; methyl salicylate; palladium on activated charcoal; In ethanol; acetonitrile;

DOI:10.1016/S0960-894X(99)00220-6

upstream raw materials:

trisylhydrazine

1-[(3S,5R,8R,9R,10R,13R,14R,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethanone

20-ξ(2)-Hydroxy-3-oxo-dammaren-(24); Dipterocarpol

'Dammarendiol'