N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide

Base Information

• Chemical Name: N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide
• CAS No.: 1138241-94-7
• Molecular Formula: C₂₂H₁₉BrN₂O₄
• Molecular Weight: 455.308
• Mol file: 1138241-94-7.mol

Synonyms:N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide

Chemical Property of N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide

There total 1 articles about N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H13BrClNO4 + dimethyl amine (124-40-3) → N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide (1138241-94-7)

Guidance literature:

In water; benzene; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tet.2009.01.011

Reference yield: 78.0%

N,N-dimethyl{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}glyoxylamide (1138241-94-7) → N,N-dimethyl 2-{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}-2-hydroxyacetamide (1138242-04-2)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; ethanol; at 0 - 20 ℃; for 0.75h;

DOI:10.1016/j.tet.2009.01.011

upstream raw materials:

dimethyl amine

Downstream raw materials:

N,N-dimethyl 2-{1-(4'-bromophenyl)-6,8-dimethoxy-pyrrolo[3,2,1-hi]indol-2-yl}-2-hydroxyacetamide